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The infection rate in South Africa when this variant arose was extremely low. This variant has not had to compete with Delta at all. It established itself in
by lamontcg 5y ago
The infection rate in South Africa when this variant arose was extremely low.
This variant has not had to compete with Delta at all.
It established itself in a vacuum of infections, and it may all be due to founder effects, with a new wave of infections due to behavior or other changes.
I'm also very skeptical that P681H is suddenly going to flip the script and start displacing P681R.
SA also has low vaccination rates and its not obvious that this variant arose because of selection for immune evasion (even if it did, immune evasion from NAbs is probably inevitable and will happen forever).