3 ms·

A Smart Artificial Pancreas Could Conquer Diabetes

27 points by rchaudhary 5y ago

onemoresoop 5y ago
Good news. Let's just hope artificial organs don't fall into the same software trap of dark patters as of late: privacy issues, bad firmware updates and bad security vulnerabilities. So no Wi-Fi or Bluetooth, okay? And no data logging that is sent directly to insurance companies..
- Terry_Roll 5y ago
  Vit K1 can already make you more insulin sensitive and can even have positive effects on induced Type 1 diabetes. Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-κB activation and iNOS expression in rat pancreas https://www.sciencedirect.com/science/article/abs/pii/S0899900714002792 https://www.sciencedirect.com/science/article/abs/pii/S08999... Its incredibly difficult getting hold of any sizable (pharmacological) amounts of K1 for reasonable money. I didn't realise good health is so expensive.
- pkaye 5y ago
  Luckily the artificial kidney turned out to be a passive device. As a dialysis patient it sucks that its so little funded and taking long to progress. https://pharm.ucsf.edu/kidney https://pharm.ucsf.edu/kidney
- mysterydip 5y ago
  "Can't afford your pancreas subscription? AstraZeneca may be able to help."
deleted 5y ago
[deleted]
aviau 5y ago
I would like to add that Control-IQ still underperforms open source DIY artificial pancreas systems like Loop (https://github.com/LoopKit/Loop https://github.com/LoopKit/Loop). The guys that built Loop and the Riley Link (https://getrileylink.org/ https://getrileylink.org/) (bluetooth to RF adapter relay to control wireless pumps that were reverse-engineered) are heroes.
chestertn 5y ago
Has anybody read about insuline resistance?
- SketchySeaBeast 5y ago
  Yes, and in the case of these tools it's probably not relevant for the majority of cases - if you're a type 1 diabetic you don't produce enough insulin, it's not a question of how resistant you are to it.
dang 5y ago
https://news.ycombinator.com/item?id=29300881 https://news.ycombinator.com/item?id=29300881

27 points by rchaudhary 5y ago

Good news. Let's just hope artificial organs don't fall into the same software trap of dark patters as of late: privacy issues, bad firmware updates and bad security vulnerabilities. So no Wi-Fi or Bluetooth, okay? And no data logging that is sent directly to insurance companies..

Terry_Roll 5y ago
Vit K1 can already make you more insulin sensitive and can even have positive effects on induced Type 1 diabetes. Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-κB activation and iNOS expression in rat pancreas https://www.sciencedirect.com/science/article/abs/pii/S0899900714002792 https://www.sciencedirect.com/science/article/abs/pii/S08999... Its incredibly difficult getting hold of any sizable (pharmacological) amounts of K1 for reasonable money. I didn't realise good health is so expensive.
pkaye 5y ago
Luckily the artificial kidney turned out to be a passive device. As a dialysis patient it sucks that its so little funded and taking long to progress. https://pharm.ucsf.edu/kidney https://pharm.ucsf.edu/kidney
mysterydip 5y ago
"Can't afford your pancreas subscription? AstraZeneca may be able to help."

deleted 5y ago

[deleted]

aviau 5y ago

I would like to add that Control-IQ still underperforms open source DIY artificial pancreas systems like Loop (https://github.com/LoopKit/Loop https://github.com/LoopKit/Loop). The guys that built Loop and the Riley Link (https://getrileylink.org/ https://getrileylink.org/) (bluetooth to RF adapter relay to control wireless pumps that were reverse-engineered) are heroes.

chestertn 5y ago

Has anybody read about insuline resistance?

SketchySeaBeast 5y ago
Yes, and in the case of these tools it's probably not relevant for the majority of cases - if you're a type 1 diabetic you don't produce enough insulin, it's not a question of how resistant you are to it.

dang 5y ago

https://news.ycombinator.com/item?id=29300881 https://news.ycombinator.com/item?id=29300881