3 ms·
Cocaine also induces microischemia - basically constricts your capillaries and starves the neurons/glia of oxygen. This happens slowly over time and is cumulati
by kortex 5y ago
Cocaine also induces microischemia - basically constricts your capillaries and starves the neurons/glia of oxygen. This happens slowly over time and is cumulative.
As mentioned, coke is high on the abuse potential scale due to its rapid onset and withdrawal, short loop between behavior and reward.
https://www.pbs.org/newshour/science/brains-blood-cocaine https://www.pbs.org/newshour/science/brains-blood-cocaine
- ycombinete 5y agoNot to mention that people are highly functional while high on it. So there’s no downtime on when you can be high.
- runnerup 5y agoAlcohol also causes ischemia. Prescription amphetamines also cause ischemia but are legal. > As mentioned, coke is high on the abuse potential scale due to its rapid onset and withdrawal, short loop between behavior and reward. I wonder if attaching an amino acid (a la Vyvanse) would improve its pharmacokinetic profile to reduce this addiction potential. We'll never know, because its not legal to do research on medical potential for Schedule I drugs.