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City of Hope Medical Center is developing the PIpepTolDC "inverse vaccine" to treat Type 1 Diabetes and other auto-immune diseases [0]. They have had two succe
by mleonhard 5y ago
City of Hope Medical Center is developing the PIpepTolDC "inverse vaccine" to treat Type 1 Diabetes and other auto-immune diseases [0]. They have had two successful trials in humans. The third trial is recruiting [1].
The PIpepTolDC treatment is expensive because it is labor intensive. A technician must take some of the patient's blood, isolate their immune cells, replicate the cells, desensitize them, and then inject them back into the patient. BioNTech's treatment is a simple injection and should be inexpensive.
[0] https://www.precisionvaccinations.com/type-1-diabetes-vaccine-candidate-launches-usa-study https://www.precisionvaccinations.com/type-1-diabetes-vaccin...
[1] https://clinicaltrials.gov/ct2/show/NCT04590872 https://clinicaltrials.gov/ct2/show/NCT04590872