3 ms·

Applaud her efforts. Another way is to just take a bunch of mushrooms.

datameta 5y ago
Set, setting, cast, and dose are hugely important. It is proven in clinical settings. On one's own, doing a smaller dose for the first time with friends in nice weather with minimal stressors can be a huge learning experience and an enjoyable journey.
- MarcoZavala 5y ago
encryptluks2 5y ago
Definitely don't recommend without knowing yourself, and even then it can be dangerous. I once watched someone try mushrooms for their first time try to harm themselves and thankfully I was there to help them through it, but they had some underlying issues that were unknown and were only exacerbated by the pyschedelics.
Terry_Roll 5y ago
Hot off the press. Oct 2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868946/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868946/ Its thought the Psilocybin caps the serotonin receptors constantly stimulating them in much the same way SSRI's work but this approach may still have its pitfalls. https://www.vice.com/en/article/pkeqd8/what-happens-lsd-overdose https://www.vice.com/en/article/pkeqd8/what-happens-lsd-over... If you want a good legal laugh, swap sugar for Glycine, its found in sugar cane anyway, about 22% of it is glycine, so spoon it into your hot beverages, sprinkle it on your food and sit back and enjoy like your haven't laughed since you were kid! You will also smell nicer. Word of warning, you might get into trouble laughing at things that require a sombre or serious attitude so dont blame me if you get sacked from your job! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955867/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955867/
- fbanon 5y ago
  "The LD50 of glycine is 7930 mg/kg in rats (oral), and it usually causes death by hyperexcitability."
  - Terry_Roll 5y ago
    What you are doing with Glycine is ramping up the 5 Alpha Reductase to upregulate these conversions in the body. https://en.wikipedia.org/wiki/5%CE%B1-Reductase#List_of_conversions https://en.wikipedia.org/wiki/5%CE%B1-Reductase#List_of_conv... Some SSRI's, not all, also work with Glycine in the brain. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697779/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697779/ Depression can be caused by too much stress, too much cortisol is not good for us. There are obviously other actions taking place in the body with Glycine, just like all chemicals perform multiple actions in the body, so nothing is a panacea. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/ https://www.nature.com/articles/srep10434 https://www.nature.com/articles/srep10434

Set, setting, cast, and dose are hugely important. It is proven in clinical settings. On one's own, doing a smaller dose for the first time with friends in nice weather with minimal stressors can be a huge learning experience and an enjoyable journey.

MarcoZavala 5y ago

encryptluks2 5y ago

Definitely don't recommend without knowing yourself, and even then it can be dangerous. I once watched someone try mushrooms for their first time try to harm themselves and thankfully I was there to help them through it, but they had some underlying issues that were unknown and were only exacerbated by the pyschedelics.

Terry_Roll 5y ago

Hot off the press. Oct 2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868946/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868946/ Its thought the Psilocybin caps the serotonin receptors constantly stimulating them in much the same way SSRI's work but this approach may still have its pitfalls. https://www.vice.com/en/article/pkeqd8/what-happens-lsd-overdose https://www.vice.com/en/article/pkeqd8/what-happens-lsd-over... If you want a good legal laugh, swap sugar for Glycine, its found in sugar cane anyway, about 22% of it is glycine, so spoon it into your hot beverages, sprinkle it on your food and sit back and enjoy like your haven't laughed since you were kid! You will also smell nicer. Word of warning, you might get into trouble laughing at things that require a sombre or serious attitude so dont blame me if you get sacked from your job! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955867/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955867/

fbanon 5y ago
"The LD50 of glycine is 7930 mg/kg in rats (oral), and it usually causes death by hyperexcitability."
- Terry_Roll 5y ago
  What you are doing with Glycine is ramping up the 5 Alpha Reductase to upregulate these conversions in the body. https://en.wikipedia.org/wiki/5%CE%B1-Reductase#List_of_conversions https://en.wikipedia.org/wiki/5%CE%B1-Reductase#List_of_conv... Some SSRI's, not all, also work with Glycine in the brain. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697779/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697779/ Depression can be caused by too much stress, too much cortisol is not good for us. There are obviously other actions taking place in the body with Glycine, just like all chemicals perform multiple actions in the body, so nothing is a panacea. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/ https://www.nature.com/articles/srep10434 https://www.nature.com/articles/srep10434