If it's correctly microdosed the acutely noticed affects should be very close to placebo. For lsd this is generally under 15~20ug, though 5ug/10ug is generally

If it's correctly microdosed the acutely noticed affects should be very close to placebo. For lsd this is generally under 15~20ug, though 5ug/10ug is generally what people dose at. These dosages aren't well established with "proper studies" but I can say that people documenting there experiences seem to establish this pretty well. The psychonauts wiki is a good place for this type of information