3 ms·
At the microdose level the obvious hallucinatory effects of psychedelics are not present, so I'd imagine those without prior experience with psychedelics wouldn
by photochemsyn 5y ago
At the microdose level the obvious hallucinatory effects of psychedelics are not present, so I'd imagine those without prior experience with psychedelics wouldn't immediately realize they had taken an SSRI or a psychedelic.
The above comment study is pretty interesting, points to equivalent effectiveness.
- snikeris 5y agoYeah, it was interesting that they phrased the conclusion negatively: > On the basis of the change in depression scores on the QIDS-SR-16 at week 6, this trial did not show a significant difference in antidepressant effects between psilocybin and escitalopram in a selected group of patients. Secondary outcomes generally favored psilocybin over escitalopram, but the analyses of these outcomes lacked correction for multiple comparisons. Larger and longer trials are required to compare psilocybin with established antidepressants. For no significant difference in outcome, I'd much rather have two psilocybin sessions versus daily SSRI use.