4 ms·

Disclosure: Haven't read the paper yet, time constraints... One think pointed out when I stumbled about similar papers before was: The reduction of depression

Disclosure: Haven't read the paper yet, time constraints... One think pointed out when I stumbled about similar papers before was: The reduction of depression, anxiety, stress from micro-dosing are rediculus small compared to the effects of a more healthy live style and environment. Even just taking a walk in nature for 10min a day often had many times stronger positive effects.

gunshai 5y ago
Anecdotally I've seen these effects in someone I care about. They live a very healthy life and do all the other stuff well, but still no effect. They take one medium dose of psychedelics and are transformed for weeks. The effects do wear off. That effect by the way is the extremely esoteric "feeling openness". It is night and day for how they feel socially. I also have not read this study yet judging from a few comments it's not really randomized or blinded or anything.so the takeaways are very minimal.
- throwamon 5y ago
  > They take one medium dose of psychedelics and are transformed for weeks How much is this "medium dose"? In all likelihood it's not a microdose, which is what is under discussion. It's well known that higher doses can have lasting effects.
  - gunshai 5y ago
    You are correct that this isn't in the realm of micro. I was more speaking to the substance than the dose.
- Dumblydorr 5y ago
  I don't think feeling openness is extremely esoteric. One of the five basic personality traits is Open-Mindedness. It allows us to accept data with less bias, prediction, and judgment. It allows us to refresh our browsers, clear our cache, and garbage collect our minds. Open-Mindedness is a wonderful trait that everyone should cultivate.
stronglikedan 5y ago
I walk at least two miles a day outside, every day, and have for years. I'm in the middle of a bout of depression, and I was having a very hard time focusing on work while at work. I've been microdosing for two weeks now, and I've noticed a huge increase in my productivity at work, as well as my general mood. I guess what I'm trying to say is that regular exercise/nature can only get me so far, and even a ridiculously small improvement from psilocybin has been a game changer to me. So, why not both?
- lostmsu 5y ago
  Almost 100% of people who increase their consumption of cucumbers during common cold feel significantly better after two weeks. Maybe cucumbers work for depression too. You should check them out.
  - the-dude 5y ago
    This is unneccessarly snarky and disrespectful.
    - lostmsu 5y ago
      Posting low quality anecdata on drugs is disrespectful for the time of people who can validate the data quality, and outright dangerous for the people who can not.
      - mistermann 5y ago
        I'm curious what evidence or reasoning you could offer to substantiate each of these claims.
        lostmsu 5y ago
        What part of these two claims you find doubtful exactly? Respect part is about wasting people's time (if knowingly). The danger part is the same as with any other misleading information, which can lead people to consume damaging amounts of dangerous substances for now good reason (at least not better than just eating cucumbers instead).

gunshai 5y ago

Anecdotally I've seen these effects in someone I care about. They live a very healthy life and do all the other stuff well, but still no effect. They take one medium dose of psychedelics and are transformed for weeks. The effects do wear off. That effect by the way is the extremely esoteric "feeling openness". It is night and day for how they feel socially. I also have not read this study yet judging from a few comments it's not really randomized or blinded or anything.so the takeaways are very minimal.

throwamon 5y ago
> They take one medium dose of psychedelics and are transformed for weeks How much is this "medium dose"? In all likelihood it's not a microdose, which is what is under discussion. It's well known that higher doses can have lasting effects.
- gunshai 5y ago
  You are correct that this isn't in the realm of micro. I was more speaking to the substance than the dose.
Dumblydorr 5y ago
I don't think feeling openness is extremely esoteric. One of the five basic personality traits is Open-Mindedness. It allows us to accept data with less bias, prediction, and judgment. It allows us to refresh our browsers, clear our cache, and garbage collect our minds. Open-Mindedness is a wonderful trait that everyone should cultivate.

stronglikedan 5y ago

I walk at least two miles a day outside, every day, and have for years. I'm in the middle of a bout of depression, and I was having a very hard time focusing on work while at work. I've been microdosing for two weeks now, and I've noticed a huge increase in my productivity at work, as well as my general mood. I guess what I'm trying to say is that regular exercise/nature can only get me so far, and even a ridiculously small improvement from psilocybin has been a game changer to me. So, why not both?

lostmsu 5y ago
Almost 100% of people who increase their consumption of cucumbers during common cold feel significantly better after two weeks. Maybe cucumbers work for depression too. You should check them out.
- the-dude 5y ago
  This is unneccessarly snarky and disrespectful.
  - lostmsu 5y ago
    Posting low quality anecdata on drugs is disrespectful for the time of people who can validate the data quality, and outright dangerous for the people who can not.
    - mistermann 5y ago
      I'm curious what evidence or reasoning you could offer to substantiate each of these claims.
      - lostmsu 5y ago
        What part of these two claims you find doubtful exactly? Respect part is about wasting people's time (if knowingly). The danger part is the same as with any other misleading information, which can lead people to consume damaging amounts of dangerous substances for now good reason (at least not better than just eating cucumbers instead).