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I'd be careful though. Psychedelic are a powerful eye opener that can and do help with depression, but taking them regularly, even just a microdose can be a ver

I'd be careful though. Psychedelic are a powerful eye opener that can and do help with depression, but taking them regularly, even just a microdose can be a very reckless thing. They have the potential to completely drive you insane if you over do it and are best enjoyed with long intervals in between.

stronglikedan 5y ago
You're just parroting an old wive's tale designed to warn children away from drugs, despite being complete fiction.
- Forbo 5y ago
  HPPD and substance-induced psychosis are very real, however I don't know of any cases that were the result of microdosing.
- Loveaway 5y ago
  There's a difference between taking drugs and taking them every day, becoming reliant on them, considering we're talking about hallucinogenics here.
- i_like_apis 5y ago
  You think LSD induced psychosis is not a thing?
  - akomtu 5y ago
    The right question is "how often does LSD cause psychosis?"
    - i_like_apis 5y ago
      Every time you take it? It's basically a window into a malfunctioning brain. You bounce back when it wears off, but you can definitely change from tripping too much. Have you never met someone who has done too much acid?
gunshai 5y ago
Can you cite anything that shows these drugs drive you insane with regular use. That sounds like mythology.
- i_like_apis 5y ago
  > Can you cite anything that shows these drugs drive you insane with regular use. That sounds like mythology. Take a drive down skid row. Or look at Haight-Ashbury in the 70's.
  - gunshai 5y ago
    I have no idea how to take this comment. What does that have to do with psychedelics or really anything related to the topic at all.
    - i_like_apis 5y ago
      We're talking about the impact of drug use on mental health. I'm saying: look at the homeless epidemic. 90% of those folks have substance abuse issues. If you've done any psychedelics you would be foolish to not notice that they can drive a person insane under the right circumstances.
      - gunshai 5y ago
        Would I be foolish, or do I just need to be convinced with better evidence? You seem to be using a gateway type drug analogy combined with anecdote mixed with all sorts of other factors. And no I wasn't talking about "drugs" I was talking about psychedelics and their targeted use/dosage. I made the counter claim to provide evidence that psychedelics cause permanent psychosis. No one seems to be able to produce such evidence, and your point of casually linking homelessness to drug use may be all fine in a grand sense but with respect to the topic at hand it just looks like a red herring.
        i_like_apis 5y ago
luckydata 5y ago
where did you get that from?
pengaru 5y ago
> best enjoyed with long intervals in between This has zero relevance to microdosing.
Dumblydorr 5y ago
Where is your evidence that they drove people completely insane? I'm not doubting there are serious potential side effects, but the description "completely drive you insane" is a bit vague to me.
- cwkoss 5y ago
  Have you ever hung out with someone who has taken recreational dose LSD several times per week for months? I know two people who did this, and they both got very weird and ended up putting themselves in dangerous situations from their questionable judgement, years after they stopped even. One flipped his car while drunk and tripping and got seriously injured, but he made serious lifestyle changes. Months later he had a psychotic break and got arrested naked in the street. He is mostly better however he is still a shell of his former self. The other ended up getting addicted to heroin and overdosed several years later. Could just be selection bias and clustering of risky behaviors, but I believe the LSD played some role (possibly related to an interaction between LSD and SSRIs). I think there are a lot of potential therapeutic benefits that should be studied, but clandestine microdosing is still risky as its practically impossible dose accurately and many people who think they are microdosing are taking doses that exceed the perceptual threshold because they don't think it's working if they don't feel it. Taking 5mcg LSD 3x week is probably mostly safe. Taking 40mcg once a quarter is also probably mostly safe. Taking an unknown 10-40 mcg 3x week seems like it could be entering the danger zone. (Please learn about volumetric dosing if you're considering microdosing - it at least allows consistency. Fractions of blotter are inherently inconsistent because blotter concentration is not homogenous.)
  - chasebank 5y ago
    "Have you ever hung out with someone who has taken recreational dose LSD several times per week for months?" Yes. He's a pretty normal dude.
- l33tbro 5y ago
  If people here are seriously asking for evidence-based proof that acid can destroy people, then they are not very old or have survived partying / rave scenes. The term "acid casualty" exists for a reason. I've known a few people that over-indulged and became detached weirdos and never came back. It's not a 'wives tale' as someone here said. Take acid by all means. Just know that you could become a despondent ghoul if you go too hard and frequently.

stronglikedan 5y ago

You're just parroting an old wive's tale designed to warn children away from drugs, despite being complete fiction.

Forbo 5y ago
HPPD and substance-induced psychosis are very real, however I don't know of any cases that were the result of microdosing.
Loveaway 5y ago
There's a difference between taking drugs and taking them every day, becoming reliant on them, considering we're talking about hallucinogenics here.
i_like_apis 5y ago
You think LSD induced psychosis is not a thing?
- akomtu 5y ago
  The right question is "how often does LSD cause psychosis?"
  - i_like_apis 5y ago
    Every time you take it? It's basically a window into a malfunctioning brain. You bounce back when it wears off, but you can definitely change from tripping too much. Have you never met someone who has done too much acid?

gunshai 5y ago

Can you cite anything that shows these drugs drive you insane with regular use. That sounds like mythology.

i_like_apis 5y ago
> Can you cite anything that shows these drugs drive you insane with regular use. That sounds like mythology. Take a drive down skid row. Or look at Haight-Ashbury in the 70's.
- gunshai 5y ago
  I have no idea how to take this comment. What does that have to do with psychedelics or really anything related to the topic at all.
  - i_like_apis 5y ago
    We're talking about the impact of drug use on mental health. I'm saying: look at the homeless epidemic. 90% of those folks have substance abuse issues. If you've done any psychedelics you would be foolish to not notice that they can drive a person insane under the right circumstances.
    - gunshai 5y ago
      Would I be foolish, or do I just need to be convinced with better evidence? You seem to be using a gateway type drug analogy combined with anecdote mixed with all sorts of other factors. And no I wasn't talking about "drugs" I was talking about psychedelics and their targeted use/dosage. I made the counter claim to provide evidence that psychedelics cause permanent psychosis. No one seems to be able to produce such evidence, and your point of casually linking homelessness to drug use may be all fine in a grand sense but with respect to the topic at hand it just looks like a red herring.
      - i_like_apis 5y ago

luckydata 5y ago

where did you get that from?

pengaru 5y ago

> best enjoyed with long intervals in between This has zero relevance to microdosing.

Dumblydorr 5y ago

Where is your evidence that they drove people completely insane? I'm not doubting there are serious potential side effects, but the description "completely drive you insane" is a bit vague to me.

cwkoss 5y ago
Have you ever hung out with someone who has taken recreational dose LSD several times per week for months? I know two people who did this, and they both got very weird and ended up putting themselves in dangerous situations from their questionable judgement, years after they stopped even. One flipped his car while drunk and tripping and got seriously injured, but he made serious lifestyle changes. Months later he had a psychotic break and got arrested naked in the street. He is mostly better however he is still a shell of his former self. The other ended up getting addicted to heroin and overdosed several years later. Could just be selection bias and clustering of risky behaviors, but I believe the LSD played some role (possibly related to an interaction between LSD and SSRIs). I think there are a lot of potential therapeutic benefits that should be studied, but clandestine microdosing is still risky as its practically impossible dose accurately and many people who think they are microdosing are taking doses that exceed the perceptual threshold because they don't think it's working if they don't feel it. Taking 5mcg LSD 3x week is probably mostly safe. Taking 40mcg once a quarter is also probably mostly safe. Taking an unknown 10-40 mcg 3x week seems like it could be entering the danger zone. (Please learn about volumetric dosing if you're considering microdosing - it at least allows consistency. Fractions of blotter are inherently inconsistent because blotter concentration is not homogenous.)
- chasebank 5y ago
  "Have you ever hung out with someone who has taken recreational dose LSD several times per week for months?" Yes. He's a pretty normal dude.
l33tbro 5y ago
If people here are seriously asking for evidence-based proof that acid can destroy people, then they are not very old or have survived partying / rave scenes. The term "acid casualty" exists for a reason. I've known a few people that over-indulged and became detached weirdos and never came back. It's not a 'wives tale' as someone here said. Take acid by all means. Just know that you could become a despondent ghoul if you go too hard and frequently.