It's more that the designs you're likely to be building to take advantage of the fancy extruder are more likely to be the sort of thin-shell construction where

It's more that the designs you're likely to be building to take advantage of the fancy extruder are more likely to be the sort of thin-shell construction where holes anywhere cause structural issues that you wouldn't see with more discrete building elements. I was also thinking that if you've only got a hole in one face of a wall, you can't get to the back of the hole to support a patch, but I'm guessing that's less of a problem.