I think this actually gets to the crux of the matter. The existing python dependency management tools (especially the new shiny ones like poetry) are very much

I think this actually gets to the crux of the matter. The existing python dependency management tools (especially the new shiny ones like poetry) are very much designed by python devs, for python devs. What you're describing is a totally different use case, which is running released software in a sensible way. The distro package managers are probably the best place for that, but bridging the gap between them and the python ecosystem is an obvious challenge.