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There's a great video from a professor at Stanford, Robert Sapolsky, about depression, where he dives into the biological and psychological aspect of depression
by kklisura 5y ago
There's a great video from a professor at Stanford, Robert Sapolsky, about depression, where he dives into the biological and psychological aspect of depression. [1]
> If I had to define major depression in one sentence, I would say, it’s a lot biochemical disorder with a genetic component, and early experience influences, where somebody can’t appreciate sunsets. And that’s what this disease is about.
[1] (2009, youtube) https://www.youtube.com/watch?v=NOAgplgTxfc https://www.youtube.com/watch?v=NOAgplgTxfc
- podgaj 5y agoWe have come a long way since 2009: https://www.sciencedirect.com/science/article/abs/pii/S1089860320301993 https://www.sciencedirect.com/science/article/abs/pii/S10898... What Sapolsky was talking about was correct, but the fundamental driver seems to be oxidative stress imbalance. And the genetics part might be highly associated with the mitochondria: https://www.nature.com/articles/s41380-021-01268-x https://www.nature.com/articles/s41380-021-01268-x