I like the global state of mind idea, however, I feel that it isn't purely due to this state - I think the depressive state is something that comes around due t

I like the global state of mind idea, however, I feel that it isn't purely due to this state - I think the depressive state is something that comes around due to lots of other factors such as your life, your health, your physical brain composition. So it's almost like, if your environment and health are bad your consciousness will be more "magnetised" towards a global depressive state, and whilst psychedelics may help awaken you, you'll be more likely to slip back into it in time without fixing other stuff. Psychedelics may be a temporary cure to crushing hopelessness, a kick in the mental butt, but for a one that is long lasting you have to have things to be genuinely hopeful about. Depression I think is a complex, multi-dimensional issue that has to be solved by giving yourself the best chance across the board - sorting out health, sorting out meaning and purpose, sorting out social and support networks, and once those things are in place, taking your shot at it on a brain chemistry and consciousness-altering level with something like psiloscibin etc.