3 ms·
This study does not report that that layer V cortical neurons are missing a particular ion channel. They examine currents through HCN and voltaged-gated potassi
by disco_nap 5y ago
This study does not report that that layer V cortical neurons are missing a particular ion channel. They examine currents through HCN and voltaged-gated potassium channels and find differences in the total current carried that depends on species.
In general, epileptic disorders are observed across species. It's common in dogs, for instance: https://www.akcchf.org/canine-health/top-health-concerns/epilepsy/understanding-canine-epilepsy.html https://www.akcchf.org/canine-health/top-health-concerns/epi...
A ton of papers examining ion channel expression in epilepsy that should be more relevant:
https://pubmed.ncbi.nlm.nih.gov/?term=human+ion+channel+epilespy https://pubmed.ncbi.nlm.nih.gov/?term=human+ion+channel+epil...