3 ms·

Can you clarify why people should avoid physical exertion in the 14 day window? Also, is there currently any evidence that your immune system is generally less

Can you clarify why people should avoid physical exertion in the 14 day window? Also, is there currently any evidence that your immune system is generally less effective during that time?

walterbell 5y ago
> Can you clarify why people should avoid physical exertion in the 14 day window? Some countries issued a warning about myocarditis. This was later narrowed to young people. Some countries later banned Moderna entirely for young people. There was also a concern about transient blood clots or micro-clots (also possible with Covid itself), which can impact blood circulation. > is there currently any evidence that your immune system is generally less effective during that time? In addition to anecdotal reports from doctors, here are 2 short papers. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379763/pdf/main.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379763/pdf/mai... > Our case report describes two adults developing herpes zoster after vaccination with tozinameran (the Pfizer- BioNTech COVID-19 mRNA vaccine). A possible cause for this reaction is a transient lymphocytopenia that occurs after the vaccination — similar to that in COVID-19 disease https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8546144/pdf/41421_2021_Article_329.pdf https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8546144/pd... > we report, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an inactivated SARS-CoV-2 vaccine. Similar changes had also been reported in COVID-19 patients, suggesting that vaccination mimicked an infection As with all adverse events which may or may not be related to vaccines, we need more funding to investigate reports, identify common factors in those who were affected, then construct studies, testing and surveillance to differentiate cause from coincidence.

Can you clarify why people should avoid physical exertion in the 14 day window? Also, is there currently any evidence that your immune system is generally less effective during that time?

walterbell 5y ago

> Can you clarify why people should avoid physical exertion in the 14 day window? Some countries issued a warning about myocarditis. This was later narrowed to young people. Some countries later banned Moderna entirely for young people. There was also a concern about transient blood clots or micro-clots (also possible with Covid itself), which can impact blood circulation. > is there currently any evidence that your immune system is generally less effective during that time? In addition to anecdotal reports from doctors, here are 2 short papers. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379763/pdf/main.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379763/pdf/mai... > Our case report describes two adults developing herpes zoster after vaccination with tozinameran (the Pfizer- BioNTech COVID-19 mRNA vaccine). A possible cause for this reaction is a transient lymphocytopenia that occurs after the vaccination — similar to that in COVID-19 disease https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8546144/pdf/41421_2021_Article_329.pdf https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8546144/pd... > we report, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an inactivated SARS-CoV-2 vaccine. Similar changes had also been reported in COVID-19 patients, suggesting that vaccination mimicked an infection As with all adverse events which may or may not be related to vaccines, we need more funding to investigate reports, identify common factors in those who were affected, then construct studies, testing and surveillance to differentiate cause from coincidence.