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What makes for a good radiosensitizer? It seems gold is pretty popular at the moment as well, so curious what properties in particular are amenable to rendering
by panabee 5y ago
What makes for a good radiosensitizer? It seems gold is pretty popular at the moment as well, so curious what properties in particular are amenable to rendering a substance a good radiosensitizer?
Thanks for sharing!
- sniperjoe360 5y agoThe only FDA approved radiosensitizers are chemotherapy based (i.e. platinum, taxol). Vitamin B3 (Niacin) is a weak radiosensitizer at large doses. Finally hyperthermia and increase atmospheric O2 also increase radiosensitivity. The common pathway they are theorized to work though is increasing reactive oxygen species. More reactive oxygen species, the more DNA damage, which leads to cell kill.