For me, I get depressed when I feel "stuck" in my circumstances (mostly a directionless project, bad boss, or cancerous working environment, or all of the above

For me, I get depressed when I feel "stuck" in my circumstances (mostly a directionless project, bad boss, or cancerous working environment, or all of the above). I suppose going on a "trip" would alleviate that significantly, at least for a while. Then you'll get used to it and you'll be back to square one you can't escape without fixing the root cause. So any enthusiasm for this is going to have to be tempered by long term studies and outcomes. Any significant change in one's circumstances can _tactically_ alleviate depression somewhat.