3 ms·
That's a good point, I was wondering about the dose myself but I couldn't assess it. Seems like we might be off by a few orders of magnitude here. Edit: I've
by incrudible 5y ago
That's a good point, I was wondering about the dose myself but I couldn't assess it. Seems like we might be off by a few orders of magnitude here.
Edit:
I've looked at the link provided:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172803/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172803/
These numbers are not as far off (within a single order of magnitude) as the ones Lowe cites, but definitely outside the realm of "generally considered safe" dose. That's for the mechanism discussed there, where the IC50 was only 2µM.
Translated to the "protease inhibitor" scenario discussed in the video, it's way off. The IC50 there is 21µM. At only 2µM the effect is negligible.