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Why is a multivitamin complex necessary after large doses of B vitamins? I thought that B vitamins are just water-soluble and your body removes the excess.
by DarknessFalls 5y ago
Why is a multivitamin complex necessary after large doses of B vitamins? I thought that B vitamins are just water-soluble and your body removes the excess.
- garganzol 5y agoVitamins are catalysts of chemical reactions. When you speed up reactions dependent on, say, B1 - you should also be sure that adjacent reactions are fastened up. Otherwise, this may cause an imbalance which can be disastrous or even fatal. The same rule goes to minerals - when you take vitamins, the reaction speeds increase and they start to consume significantly more substrates causing electrolyte disbalances, which can be disastrous and even fatal. That's why you have to make sure that you take enough of Mg, K, P when you get vitamins as well.
- podgaj 5y agoAs an example I will show how taking his dose riboflavin might increase the need for Zinc and Magnesium. To turn Riboflavin into FMN using an enzyme called RFK, which needs zinc and magnesium as cofactors: https://www.uniprot.org/uniprot/Q969G6 https://www.uniprot.org/uniprot/Q969G6 The it turns FMN to turn into FAD using FLAD1, which needs Magnesium as a cofactor. https://www.uniprot.org/uniprot/Q8NFF5 https://www.uniprot.org/uniprot/Q8NFF5