4 ms·
If you're looking for the graph(s), https://www.science.org/doi/10.1126/science.abm0620#F1 https://www.science.org/doi/10.1126/science.abm0620#F1 Vaccine-as-a
by sva_ 5y ago
If you're looking for the graph(s),
https://www.science.org/doi/10.1126/science.abm0620#F1 https://www.science.org/doi/10.1126/science.abm0620#F1
Vaccine-as-a-service it is, I guess. What a 'happy accident'.
- mjevans 5y agoThese graphs don't quite tell me enough. It's a complex problem and even with margins of error for varying health condition I'd expect at least a 3d projection to be required to map between age, time (since 'full inoculation') and risks of illness / disease / hospitalization / death. I have also heard that lifestyles which encourage sitting all day and correlate strongly with lower fitness and higher carried fat are increased risk factors. I guess I'd appreciate a formula from the FDA and CDC that tells me roughly what time frame they recommend a (regular interval?) booster shot, rather than some oversimplified coarse number.
- throwaway4good 5y agoWhy is the "VE-D" number nowhere near the original 95% efficacy number widely reported for the Pfizer/Moderna vaccines when they were originally approved? Is it different methodology or is it changed nature of the pandemic?
- rsynnott 5y agoThe major variant around during the original trials was the ancestral one (Alpha may just about have been showing up). In a way we may have been lucky here; there’s some reason to think that Beta is less susceptible to the vaccines than Delta, but Delta outcompeted it.
- nonameking2026 5y agoThis provides a good reason. Link to the bmj peer reviewed article in the show notes. https://www.youtube.com/watch?v=THv33zWykJc https://www.youtube.com/watch?v=THv33zWykJc
- News-Dog 5y agoAlso see : https://news.ycombinator.com/item?id=29346565 https://news.ycombinator.com/item?id=29346565 https://news.ycombinator.com/item?id=29208007 https://news.ycombinator.com/item?id=29208007 (New target for Covid-19 vaccines identified: https://www.ucl.ac.uk/news/2021/nov/new-target-covid-19-vaccines-identified https://www.ucl.ac.uk/news/2021/nov/new-target-covid-19-vacc...)
- martingoodson 5y agoDelta
- colechristensen 5y agoEfficacy depends on strain. Lower for some variants. Vaccines will need to be updated regularly as the virus evolves.
- drran 5y agoEfficacy != efficiency. Efficacy is just estimation after some tests. It must be at least 50% for vaccine to be accepted. 95% is bigger than 50%.
- throwaway2077 5y ago>VAAS Did I ever tell you the definition of insanity?
- xbcac 5y agoBeing glued to CNN and believing something new official truth every week would be a good definition.
- yehosef 5y agoIt's called Product-Market Fit.
- forgotmyoldname 5y agoA rapidly evolving virus rapidly evolved, to the surprise of no one who paid attention in biology class. I wonder if covid conspiracy folks also think influenza is a "happy accident" by the pharmaceutical industry.
- plantain 5y agoIt's not due to the evolution / delta variant. [1] https://www.latimes.com/science/story/2021-10-04/pfizer-covid-vaccine-waning-not-deltas-fault https://www.latimes.com/science/story/2021-10-04/pfizer-covi...
- sva_ 5y agoI don't know where you got the conspiracy idea from? You're making a baseless assumption.
- legulere 5y agoThanks for the link. There are also graphs for mortality, that show that vaccines continue to greatly reduce the probability to die of COVID-19: https://www.science.org/doi/10.1126/science.abm0620#F3 https://www.science.org/doi/10.1126/science.abm0620#F3 Combined with the reduced probability to get infected, the only thing you have to worry about is infecting the unvaccinated.