4 ms·

I don't know if ivermectin is efficient, but I doubt it has substantial side-effects. Your first link states that ivermectin is "proved to be safe at the conve

by isolli 5y ago

I don't know if ivermectin is efficient, but I doubt it has substantial side-effects. Your first link states that ivermectin is "proved to be safe at the conventional dose, although severe adverse effects have occasionally been reported". Occasional is not "substantial". Your second link does not work for me.

acdha 5y ago
The people pushing it as a COVID treatment are usually pushing prolonged usage at higher doses – they routinely dismiss studies showing no benefits as not using enough – and the documented side effects definitely happen at those levels. The lower doses used for parasite treatments also are balanced against high efficacy, whereas this just means you still have COVID along with new problems. Sorry about the link - it worked earlier when I tested it. You can try this one: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...
- isolli 5y ago
  Thanks for the updated link. What I read is: "Ivermectin has few unwanted effects." I don't think (and you also seem to imply) that any of the studies conducted for Covid were using much higher doses than the standard. On the contrary, this was precisely the point of clinical studies: to determine whether a standard dose of ivermectin (with known and limited side effects) would provide benefits, even though it is lower than the dose at which ivermectin was initially shown to have antiviral properties in vitro.
- Izkata 5y ago
  > The people pushing it as a COVID treatment are usually pushing prolonged usage at higher doses – they routinely dismiss studies showing no benefits as not using enough – and the documented side effects definitely happen at those levels. Uh, I have never seen that from them. All of them say the bad studies are the ones using too high a dosage, and the side effects from that dosage are why those studies have bad results.

by isolli 5y ago

acdha 5y ago

The people pushing it as a COVID treatment are usually pushing prolonged usage at higher doses – they routinely dismiss studies showing no benefits as not using enough – and the documented side effects definitely happen at those levels. The lower doses used for parasite treatments also are balanced against high efficacy, whereas this just means you still have COVID along with new problems. Sorry about the link - it worked earlier when I tested it. You can try this one: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...

isolli 5y ago
Thanks for the updated link. What I read is: "Ivermectin has few unwanted effects." I don't think (and you also seem to imply) that any of the studies conducted for Covid were using much higher doses than the standard. On the contrary, this was precisely the point of clinical studies: to determine whether a standard dose of ivermectin (with known and limited side effects) would provide benefits, even though it is lower than the dose at which ivermectin was initially shown to have antiviral properties in vitro.
Izkata 5y ago
> The people pushing it as a COVID treatment are usually pushing prolonged usage at higher doses – they routinely dismiss studies showing no benefits as not using enough – and the documented side effects definitely happen at those levels. Uh, I have never seen that from them. All of them say the bad studies are the ones using too high a dosage, and the side effects from that dosage are why those studies have bad results.