3 ms·

Except this is studied and dosed appropriately vs. tacking a bunch of Ivermectin and shitting your intestines out based on a half-truth you read about from Face

Except this is studied and dosed appropriately vs. tacking a bunch of Ivermectin and shitting your intestines out based on a half-truth you read about from Facebook.

dontcare007 5y ago
Like what happened with Joe Rogan, oh wait, he recovered.
- ceejayoz 5y ago
  As have people who didn't get ivermectin. As have people who didn't get any treatment. That's why we rely on data from more than one case, to figure out relative effectiveness of different treatment methods.
- HelloMcFly 5y ago
  Do you believe that to be some sort of counter-argument or opposing view for anything I said? Regardless of the answer, I'm not interested in debating the wisdom of taking dog medicine in unstudied doses for an unstudied treatment with unstudied effectiveness that has a clearly documented ability to strip the lining of your intestines. You want be a trailblazer with every Facebook remedy? Be my guest.
  - ed25519FUUU 5y ago
    You know IVM has been around since the 70s? People take it all of the time. It’s a very studied drug, on the list of WHO’s 100 most essential medicines. The inventor won the noble prize for it. The cultivated animosity towards it is more of a result of propaganda. With this much money at stake, it’s easy to see who might actually be pushing that propaganda.
    - HelloMcFly 5y ago
      Let's make it explicit: I personally know people - including one direct and one extended family member - involved in this Facebook-science culture. I have seen the videos they are following, I know they are taking the medicine for an unresearched purpose in recommended dosages without any cited scientific reasoning to support. I'm not anti-Ivermectin anymore than I'm anti-any prescribed drug. I give it to my dog. My dad has used it, under the guidance of a doctor.
cheaprentalyeti 5y ago
I lost a family member to one of those "supposedly treats Covid" drugs. It was called Remdesivir, and it had the full blessing of the people who told you Ivermectin causes you to shit your intestines out. It causes kidney failure. Just the thing for treating someone whose lungs are filling with fluid from viral pneumonia. I really wish at the time they went in the hospital (in December) that I had known the WHO had withdrawn it from their recommended treatment list the month before, in November 2020. BUT that particular piece of news was not important to the people who run the big propaganda campaign against Ivermectin.
- HelloMcFly 5y ago
  > it had the full blessing of the people who told you Ivermectin causes you to shit your intestines out... Is this a defense of Ivermectin somehow? > I really wish at the time... that I had known the WHO had withdrawn it from their recommended treatment list the month before Sounds like the people who don't endorse Ivermectin did in fact say the right thing. "The people who told you" I am referring to are doctors and health professionals, not Internet mobs.
pjkundert 5y ago
The LD50 for Ivermectin is 10mg/kg. The standard dosage range is .1-.5mg/kg. (from memory... YMMV) So, you would have to guzzle 20 times the recommended dosage of a foul-tasting elixir to get near a lethal dose. It sticks around in your system for ~4days, so there could be a cumulative effect if you guzzle enough over a few day period. But still, much less dangerous as Tylenol (toxic at 10g dose; typical therapeutic dose on the order of 1g): Paracetamol poisoning was first described in the 1960s.[6] Rates of poisoning vary significantly between regions of the world.[8] In the United States more than 100,000 cases occur a year.[1] In the United Kingdom it is the medication responsible for the greatest number of overdoses.[7] Young children are most commonly affected.[1] In the United States and the United Kingdom, paracetamol is the most common cause of acute liver failure.[9][1] And furthermore, since Ivermectin is a potent antiparasitic, many people are likely to experience Jarisch–Herxheimer reaction to the death of intestinal parasites, which indicates its working, not dangerous. So, take is slow if you also have parasites. But, by all means, carry on believing what you're told to! ;)
- HelloMcFly 5y ago
  > So, you would have to guzzle 20 times the recommended dosage of a foul-tasting elixir to get near a lethal dose. 1 This is a straw man. Lethality isn't the only negative consequence. You don't have to die to hurt yourself for no reason. > But still, much less dangerous as Tylenol Another drug I'd rarely if ever recommend taking. Could have saved you the lecture. >... many people are likely to experience Jarisch–Herxheimer reaction to the death of intestinal parasites I'm sure some are. My money is on shitting intestine lining being more likely, but whatever.

Except this is studied and dosed appropriately vs. tacking a bunch of Ivermectin and shitting your intestines out based on a half-truth you read about from Facebook.

dontcare007 5y ago

Like what happened with Joe Rogan, oh wait, he recovered.

ceejayoz 5y ago
As have people who didn't get ivermectin. As have people who didn't get any treatment. That's why we rely on data from more than one case, to figure out relative effectiveness of different treatment methods.
HelloMcFly 5y ago
Do you believe that to be some sort of counter-argument or opposing view for anything I said? Regardless of the answer, I'm not interested in debating the wisdom of taking dog medicine in unstudied doses for an unstudied treatment with unstudied effectiveness that has a clearly documented ability to strip the lining of your intestines. You want be a trailblazer with every Facebook remedy? Be my guest.
- ed25519FUUU 5y ago
  You know IVM has been around since the 70s? People take it all of the time. It’s a very studied drug, on the list of WHO’s 100 most essential medicines. The inventor won the noble prize for it. The cultivated animosity towards it is more of a result of propaganda. With this much money at stake, it’s easy to see who might actually be pushing that propaganda.
  - HelloMcFly 5y ago
    Let's make it explicit: I personally know people - including one direct and one extended family member - involved in this Facebook-science culture. I have seen the videos they are following, I know they are taking the medicine for an unresearched purpose in recommended dosages without any cited scientific reasoning to support. I'm not anti-Ivermectin anymore than I'm anti-any prescribed drug. I give it to my dog. My dad has used it, under the guidance of a doctor.

cheaprentalyeti 5y ago

I lost a family member to one of those "supposedly treats Covid" drugs. It was called Remdesivir, and it had the full blessing of the people who told you Ivermectin causes you to shit your intestines out. It causes kidney failure. Just the thing for treating someone whose lungs are filling with fluid from viral pneumonia. I really wish at the time they went in the hospital (in December) that I had known the WHO had withdrawn it from their recommended treatment list the month before, in November 2020. BUT that particular piece of news was not important to the people who run the big propaganda campaign against Ivermectin.

HelloMcFly 5y ago
> it had the full blessing of the people who told you Ivermectin causes you to shit your intestines out... Is this a defense of Ivermectin somehow? > I really wish at the time... that I had known the WHO had withdrawn it from their recommended treatment list the month before Sounds like the people who don't endorse Ivermectin did in fact say the right thing. "The people who told you" I am referring to are doctors and health professionals, not Internet mobs.

pjkundert 5y ago

The LD50 for Ivermectin is 10mg/kg. The standard dosage range is .1-.5mg/kg. (from memory... YMMV) So, you would have to guzzle 20 times the recommended dosage of a foul-tasting elixir to get near a lethal dose. It sticks around in your system for ~4days, so there could be a cumulative effect if you guzzle enough over a few day period. But still, much less dangerous as Tylenol (toxic at 10g dose; typical therapeutic dose on the order of 1g): Paracetamol poisoning was first described in the 1960s.[6] Rates of poisoning vary significantly between regions of the world.[8] In the United States more than 100,000 cases occur a year.[1] In the United Kingdom it is the medication responsible for the greatest number of overdoses.[7] Young children are most commonly affected.[1] In the United States and the United Kingdom, paracetamol is the most common cause of acute liver failure.[9][1] And furthermore, since Ivermectin is a potent antiparasitic, many people are likely to experience Jarisch–Herxheimer reaction to the death of intestinal parasites, which indicates its working, not dangerous. So, take is slow if you also have parasites. But, by all means, carry on believing what you're told to! ;)

HelloMcFly 5y ago
> So, you would have to guzzle 20 times the recommended dosage of a foul-tasting elixir to get near a lethal dose. 1 This is a straw man. Lethality isn't the only negative consequence. You don't have to die to hurt yourself for no reason. > But still, much less dangerous as Tylenol Another drug I'd rarely if ever recommend taking. Could have saved you the lecture. >... many people are likely to experience Jarisch–Herxheimer reaction to the death of intestinal parasites I'm sure some are. My money is on shitting intestine lining being more likely, but whatever.