4 ms·
The data sample is a bit low? 1200 people
by charbull 5y ago
The data sample is a bit low? 1200 people
- dragontamer 5y agoGotta prove it with 1200 before you get the funding for 10,000.
- tpxl 5y agoDepending on the effect severity you can get a representative sample from as low as 40 people (not necessarily in this case).
- spywaregorilla 5y agoThat's not low for the effect size they're observing. Note that this is a phase 2/3 trial. The safety trials have already occurred.
- roywiggins 5y agoThe effect size was very large. The calculated p-value was <0.0001. https://www.pfizer.com/news/press-release/press-release-detail/pfizers-novel-covid-19-oral-antiviral-treatment-candidate https://www.pfizer.com/news/press-release/press-release-deta...
- nonfamous 5y agoThis is a randomized clinical trial; participants are recruited into the study using methods that eliminate the biases associated with self-selected participation, like internet or TV polls. You can get statistically valid results from small samples, that apply to very broad populations, using this methodology.
- DavidPeiffer 5y agoTo mention it, not necessarily directed at you. Larger test groups are required when trying to distinguish between less effective treatments. If rabies has a 99% death rate and you try your rabies treatment on 10 people, 9 of whom live, that's much stronger evidence than a situation where 50% of people died without treatment versus 48% with treatment (sample size 100). To be confident it's not just random chance, you'll need a really large sample size for the 2nd situation.
- deleted 5y ago[deleted]