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I don't get what point you are trying to make. Yes, the vaccine efficacy drops over time. This is expected since the antibody levels in the blood drop over time
by fsh 5y ago
I don't get what point you are trying to make. Yes, the vaccine efficacy drops over time. This is expected since the antibody levels in the blood drop over time. The manufacturers have pointed out from the beginning that this drop and the potential need for a third shot have to be determined from real-world data, as was done in many studies.
Now the picture seems to be that vaccine effectiveness does indeed drop over time, but protection against severe disease remains pretty strong, with the possible exception of old people who tend to have a weak immune response. Most governments have reacted by recommending third shots to this group in order to further improve the protection.
I really can't see any controversy here. This is precisely the procedure one expects when a new vaccine is introduced.
It is also worth pointing out, that even without boosters the vaccines vastly outperform any medication tested against COVID so far. And they do that much cheaper and with lower side effects.
- angelzen 5y ago"Yes, the vaccine efficacy drops over time." That's it. Pfizer made their core of their argument to FDA for 5-11 age group based on VE against infection numbers that we agree do not hold over time. They should take their time to conduct a real study and demonstrate real clinical benefits. There is no rush.