5 ms·

Is it safe to buy this stuff over the internet/dark web? I want to try it, maybe it has nootropic effects on healthy brains too.

by fbanon 5y ago

somesortofthing 5y ago
It's an immunosuppressant, and it seems like the mechanism of action is preventing brain cell death. You'd have to be pretty old to benefit at all, and you're risking potentially fatal infection to maybe possibly get some nootropic effects. I really wouldn't risk it if I were you.
- catlikesshrimp 5y ago
  Dementia can't be cured. Best we can hope for is preventing it. So, meds agaisnt dementia will have the highest impact on populations without overt dementia
gpm 5y ago
> 3. There’s something different about how the University of Texas hospital administers calcineurin inhibitors vs. the average hospital. > This is entirely possible. Calcineurin inhibitors are dangerous and difficult to administer correctly, I know nothing about this drug... but probably not a good idea..
bencollier49 5y ago
Given that it suppresses organ rejection, my untrained speculation is that it might make you more prone to cancer.
- macNchz 5y ago
  Yes, per https://www.ncbi.nlm.nih.gov/books/NBK304321/ https://www.ncbi.nlm.nih.gov/books/NBK304321/ > There is sufficient evidence in humans for the carcinogenicity of ciclosporin. Ciclosporin causes cancer of the skin (squamous cell carcinoma), cancer at multiple other sites, and non-Hodgkin lymphoma.
InfiniteRand 5y ago
It's an immunosuppressant, so you might want to make sure you don't need your immune system too healthy before taking it ;)
- alasdair_ 5y ago
  According to my Facebook feed, All I need is to replace my immune system with Invermectin and Colloidal Silver and I’ll be fine.
klevertree 5y ago
To add to what everyone else said: it's not just an immunosuppressant, it's an immunosuppressant with unpredictable, severe side effects. It's really interesting, and I hope to reformulate it to make it possible for healthy people to use, but you will cause severe damage to yourself if you self-administer.
- TedDoesntTalk 5y ago
  Are you looking for any kind of help besides funding?
stainforth 5y ago
This also would be a hell of a stretch but the reference to the study about pigs getting hit on the head having less brain damage, maybe something in the future along these lines would be a drug football players could take during their career.

Is it safe to buy this stuff over the internet/dark web? I want to try it, maybe it has nootropic effects on healthy brains too.

by fbanon 5y ago

Is it safe to buy this stuff over the internet/dark web? I want to try it, maybe it has nootropic effects on healthy brains too.

somesortofthing 5y ago

It's an immunosuppressant, and it seems like the mechanism of action is preventing brain cell death. You'd have to be pretty old to benefit at all, and you're risking potentially fatal infection to maybe possibly get some nootropic effects. I really wouldn't risk it if I were you.

catlikesshrimp 5y ago
Dementia can't be cured. Best we can hope for is preventing it. So, meds agaisnt dementia will have the highest impact on populations without overt dementia

gpm 5y ago

> 3. There’s something different about how the University of Texas hospital administers calcineurin inhibitors vs. the average hospital. > This is entirely possible. Calcineurin inhibitors are dangerous and difficult to administer correctly, I know nothing about this drug... but probably not a good idea..

bencollier49 5y ago

Given that it suppresses organ rejection, my untrained speculation is that it might make you more prone to cancer.

macNchz 5y ago
Yes, per https://www.ncbi.nlm.nih.gov/books/NBK304321/ https://www.ncbi.nlm.nih.gov/books/NBK304321/ > There is sufficient evidence in humans for the carcinogenicity of ciclosporin. Ciclosporin causes cancer of the skin (squamous cell carcinoma), cancer at multiple other sites, and non-Hodgkin lymphoma.

InfiniteRand 5y ago

It's an immunosuppressant, so you might want to make sure you don't need your immune system too healthy before taking it ;)

alasdair_ 5y ago
According to my Facebook feed, All I need is to replace my immune system with Invermectin and Colloidal Silver and I’ll be fine.

klevertree 5y ago

To add to what everyone else said: it's not just an immunosuppressant, it's an immunosuppressant with unpredictable, severe side effects. It's really interesting, and I hope to reformulate it to make it possible for healthy people to use, but you will cause severe damage to yourself if you self-administer.

TedDoesntTalk 5y ago
Are you looking for any kind of help besides funding?

stainforth 5y ago

This also would be a hell of a stretch but the reference to the study about pigs getting hit on the head having less brain damage, maybe something in the future along these lines would be a drug football players could take during their career.