4 ms·

"Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA..." Can anyone translate?

• coldacid 5y ago
  It hangs around the DNA and makes it hard for the DNA to do its own jobs. Like a really annoying and clueless co-worker.
• jboggan 5y ago
  This is an engineering error at its heart. By design the spike protein were supposed to be expressed and embedded in the surface of the cell where they could be recognized by the immune system. Some proportion of them lingering and having any action within the cell was not foreseen.
  • kevingadd 5y ago
    Are you implying that covid-19 was engineered/designed? If not, what are you talking about?
    • Consultant32452 5y ago
      I interpreted it as referring to the spike proteins generated after receiving the mRNA vaccine. They were supposed to have been modified to not be bio-active.
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    • coldacid 5y ago
      The engineering error was on the part of the vaccine designers, choosing the spike protein as the thing to "train" our immune systems without fully understanding what the spike actually does.
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