Business domain knowledge is always a big plus. It may not be a deal-breaker. Someone who works for a web development shop or an agency can't know in advance wh

Business domain knowledge is always a big plus. It may not be a deal-breaker. Someone who works for a web development shop or an agency can't know in advance what domains they might work in, but if they can demonstrate domain expertise from previous jobs that at least shows they have the interest and ability to pick up new business domains. The least useful developers over the long term are those who focus solely on technical skills, willfully ignoring the business and its priorities and requirements.