PSSD seems to be in part mediated by desensitization of 5HTP1A receptors. Psychedelics are known to modulate 5HTP1A and increase plasticity of serotonin neurons

PSSD seems to be in part mediated by desensitization of 5HTP1A receptors. Psychedelics are known to modulate 5HTP1A and increase plasticity of serotonin neurons. This would logically be another research avenue for psychedelics. I could not find anything substantial on this specific avenue in a brief literature search, but the mechanism is there, and anecdotally people have reported success. We need to de-schedule these drugs. At the absolute minimum, we need to get rid of the vile Schd 1 "no medical uses" to allow their research to be more politically/financially palatable.