3 ms·
Moderna and Pfizer tested variant-specific (B1.351) boosters and found they weren't significantly more-effective than a third dose of the original vaccine. http
by acconsta 5y ago
Moderna and Pfizer tested variant-specific (B1.351) boosters and found they weren't significantly more-effective than a third dose of the original vaccine.
https://www.nature.com/articles/s41591-021-01527-y https://www.nature.com/articles/s41591-021-01527-y
This may of course change with new variants.
- greg5green 5y ago>found they weren't more-effective than a third dose of the original vaccine This goes against the paper: >A boost with mRNA-1273.351 appeared to be more effective at neutralization of the B.1.351 virus than a boost with mRNA-1273, evidenced by the higher mean GMT levels in the Part C cohort 1 participants (1400) than the GMT Part B participants (864) against the B.1.351 virus. Additionally, the difference between the wild-type and B.1.351 assays at day 1 dropped from 7.7-fold prior to the boost with mRNA-1273.351 to 2.6-fold at 15 days after the boost. Thank you for posting this though -- I was looking for it earlier for my own comment and couldn't find it! Bookmarking now.
- greg5green 5y agoLooking at how this commentary has gone -- why do the worse comments gets get the most traffic? And those with actual data behind them -- zero?