I lost a sister to a drug OD close to 15 yrs ago. My belief is she suffered from depression, among other things, and self medicated. That said, the opioid cris

I lost a sister to a drug OD close to 15 yrs ago. My belief is she suffered from depression, among other things, and self medicated. That said, the opioid crisis in the USA has been largerly fueled by prescription drugs. If by little guys you mean doctors, and big guys you mean the manufacturers;well there's been some progress on that. But obviously and certainly not enough. Let's also not overlook the convenient blind eye of regularors (read: government).