4 ms·

An interesting tidbit about tomatoes, and other nightshades: They contain nicotine! https://pubmed.ncbi.nlm.nih.gov/10552617/ https://pubmed.ncbi.nlm.nih.gov/1

by 0des 5y ago

An interesting tidbit about tomatoes, and other nightshades: They contain nicotine! https://pubmed.ncbi.nlm.nih.gov/10552617/ https://pubmed.ncbi.nlm.nih.gov/10552617/

deleted 5y ago
[deleted]
treeman79 5y ago
Nightshades are also inflammatory for some autoimmune conditions.
- atombender 5y ago
  Supposedly because they contain glycoalkaloids. I'm not sure who invented the Autoimmune Protocol (AIP), but it seems to have the same scientifically questionable origins as Leaky Gut Syndrome. I have yet to see any scientific evidence supporting AIP. There's one study hypothesizing that glycoalkaloids can increase/aggravate intestinal permeability (which is a real thing), but this study only looked at mice [1]. The hypothesis has not been rigorously tested in any serious clinical study on humans. [1] https://pubmed.ncbi.nlm.nih.gov/12479649/ https://pubmed.ncbi.nlm.nih.gov/12479649/
  - treeman79 5y ago
    It’s also been life changing for me and many others with Sjogrens.
  - g8oz 5y ago
    Here is one study on AIP https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647120/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647120/
  - hnzix 5y ago
    > I have yet to see any scientific evidence supporting AIP. The food elimination diet is very scientific - you add items back in one at a time to test if they cause a negative reaction to your particular physiology.
    - treeman79 5y ago
      That’s what I ended up doing. Ate nothing but sweet potatoes for a month. It was the only food I was sure didn’t cause a problem. Most boring month ever. Felt amazing at the end of it. Was shocking when I introduced things back in.
      - tmnvix 5y ago
        I've just finished a five day water fast and plan to limit my diet, introducing new types of food slowly while observing any undesirable effects. Would you mind sharing some of the foods which you found most surprising or troublesome?
        treeman79 5y ago
        Basically what is safe on AIP worked for me. Everything else is bad. Chocolate and “diet” drinks turned out to be massive migraine triggers for me. That was a big surprise
    - atombender 5y ago
      Elimination diet, sure. I meant evidence that the specific foods listed in AIP are inflammatory. I'm not contesting that it works.
colechristensen 5y ago
I am one of the rare people for which tomatoes taste like poison.
- Wistar 5y ago
  That is a shame. Although I did not much like tomatoes until I was an adult, I certainly adore them today. But it is a trade-off. Apparently I got "tomatoes taste good" in return for my "cilantro tastes toxic."
rackjack 5y ago
Tomacco? https://www.youtube.com/watch?v=Xx1ztJROpyU https://www.youtube.com/watch?v=Xx1ztJROpyU
jelliclesfarm 5y ago
Tomatoes don’t contain any alkaloids..nicotine is a very different kind of alkaloid. Tomatoes contain a diff kind of alkaloid from other nightshades. Tomatine levels drop as fruit ripens. Hardly addictive.
- jelliclesfarm 5y ago
  Having said that…if we want to talk about addictive alkaloids in our food.. Vanillin, Cocaine and Capsaicin are closely related alkaloids and all have addiction potential.
  - girvo 5y ago
    > Vanillin, Cocaine and Capsaicin are closely related alkaloids Based on which metric? Neither vanillin nor capsaicin are tropane alkaloids.
    - jelliclesfarm 5y ago
      Addictive properties in a behavioral sense are defined differently from chemical dependency. Physiological and psychoactive aspects of neural stimulation are similar among these alkaloids. Tropane structure of cocaine, scopolamine make them accumulate in liver whereas vanillin, capsaicin etc do not accumulate. Scopolamine stramonium etc are fascinating too. Datura stramonium (DS) is a widespread annual plant, containing atropine, hyoscyamine, and scopolamine, which can produce poisoning with a severe anticholinergic syndrome. In some parts of the world, ingestion of the roots, seeds or the entire plant is a trick to obtain its hallucinogenic and euphoric effects. Also was used to poison royalty and by dacoits. It also has medicinal properties. Has been recorded in medical textbooks at the time of Takshila university and in Buddhists texts. Very effective as homeopathic preparations. Jimson weed is still a common weed on road sides in America. Datura is in the same family of plants as peppers, tomatoes, potatoes and eggplants and it contains a lethal set of alkaloids. But they don’t have the same kind. Tomatoes, for example, doesn’t have any alkaloids. Only tomatine.
      - 5y ago

by 0des 5y ago

An interesting tidbit about tomatoes, and other nightshades: They contain nicotine! https://pubmed.ncbi.nlm.nih.gov/10552617/ https://pubmed.ncbi.nlm.nih.gov/10552617/

deleted 5y ago

[deleted]

treeman79 5y ago

Nightshades are also inflammatory for some autoimmune conditions.

atombender 5y ago
Supposedly because they contain glycoalkaloids. I'm not sure who invented the Autoimmune Protocol (AIP), but it seems to have the same scientifically questionable origins as Leaky Gut Syndrome. I have yet to see any scientific evidence supporting AIP. There's one study hypothesizing that glycoalkaloids can increase/aggravate intestinal permeability (which is a real thing), but this study only looked at mice [1]. The hypothesis has not been rigorously tested in any serious clinical study on humans. [1] https://pubmed.ncbi.nlm.nih.gov/12479649/ https://pubmed.ncbi.nlm.nih.gov/12479649/
- treeman79 5y ago
  It’s also been life changing for me and many others with Sjogrens.
- g8oz 5y ago
  Here is one study on AIP https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647120/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647120/
- hnzix 5y ago
  > I have yet to see any scientific evidence supporting AIP. The food elimination diet is very scientific - you add items back in one at a time to test if they cause a negative reaction to your particular physiology.
  - treeman79 5y ago
    That’s what I ended up doing. Ate nothing but sweet potatoes for a month. It was the only food I was sure didn’t cause a problem. Most boring month ever. Felt amazing at the end of it. Was shocking when I introduced things back in.
    - tmnvix 5y ago
      I've just finished a five day water fast and plan to limit my diet, introducing new types of food slowly while observing any undesirable effects. Would you mind sharing some of the foods which you found most surprising or troublesome?
      - treeman79 5y ago
        Basically what is safe on AIP worked for me. Everything else is bad. Chocolate and “diet” drinks turned out to be massive migraine triggers for me. That was a big surprise
  - atombender 5y ago
    Elimination diet, sure. I meant evidence that the specific foods listed in AIP are inflammatory. I'm not contesting that it works.

colechristensen 5y ago

I am one of the rare people for which tomatoes taste like poison.

Wistar 5y ago
That is a shame. Although I did not much like tomatoes until I was an adult, I certainly adore them today. But it is a trade-off. Apparently I got "tomatoes taste good" in return for my "cilantro tastes toxic."

rackjack 5y ago

Tomacco? https://www.youtube.com/watch?v=Xx1ztJROpyU https://www.youtube.com/watch?v=Xx1ztJROpyU

jelliclesfarm 5y ago

Tomatoes don’t contain any alkaloids..nicotine is a very different kind of alkaloid. Tomatoes contain a diff kind of alkaloid from other nightshades. Tomatine levels drop as fruit ripens. Hardly addictive.

jelliclesfarm 5y ago
Having said that…if we want to talk about addictive alkaloids in our food.. Vanillin, Cocaine and Capsaicin are closely related alkaloids and all have addiction potential.
- girvo 5y ago
  > Vanillin, Cocaine and Capsaicin are closely related alkaloids Based on which metric? Neither vanillin nor capsaicin are tropane alkaloids.
  - jelliclesfarm 5y ago
    Addictive properties in a behavioral sense are defined differently from chemical dependency. Physiological and psychoactive aspects of neural stimulation are similar among these alkaloids. Tropane structure of cocaine, scopolamine make them accumulate in liver whereas vanillin, capsaicin etc do not accumulate. Scopolamine stramonium etc are fascinating too. Datura stramonium (DS) is a widespread annual plant, containing atropine, hyoscyamine, and scopolamine, which can produce poisoning with a severe anticholinergic syndrome. In some parts of the world, ingestion of the roots, seeds or the entire plant is a trick to obtain its hallucinogenic and euphoric effects. Also was used to poison royalty and by dacoits. It also has medicinal properties. Has been recorded in medical textbooks at the time of Takshila university and in Buddhists texts. Very effective as homeopathic preparations. Jimson weed is still a common weed on road sides in America. Datura is in the same family of plants as peppers, tomatoes, potatoes and eggplants and it contains a lethal set of alkaloids. But they don’t have the same kind. Tomatoes, for example, doesn’t have any alkaloids. Only tomatine.
    - 5y ago