CJD is almost always a clinical diagnosis. MRIs and lumbar punctures give hints, but aren’t conclusive. The only way to diagnose conclusively is via a brain bi

CJD is almost always a clinical diagnosis. MRIs and lumbar punctures give hints, but aren’t conclusive. The only way to diagnose conclusively is via a brain biopsy, which apparently isn’t worth the risk in most cases. Conclusive diagnosis is often done post-mortem. (my girlfriend works in this area)