4 ms·
A reminder that these sorts of genome-wide studies are not particularly reliable due to the problem of multiple comparisons: https://www.ncbi.nlm.nih.gov/pmc/ar
by jasonhansel 5y ago
A reminder that these sorts of genome-wide studies are not particularly reliable due to the problem of multiple comparisons: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270946/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270946/
- aabaker99 5y agohttps://en.m.wikipedia.org/wiki/Bonferroni_correction https://en.m.wikipedia.org/wiki/Bonferroni_correction
- gwern 5y agoA reminder that these sorts of genome-wide studies haven't used 0.05 but genome-wide significance (10e-8 usually, and 10e-11 in OP) for a decade now for precisely that reason, and have since replicated just fine, thank you very much.