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Indeed, it seems like the mRNA vaccines got tons of traction because of a combination of high efficacy and first-mover advantage, but protein subunit vaccines l
by apendleton 5y ago
Indeed, it seems like the mRNA vaccines got tons of traction because of a combination of high efficacy and first-mover advantage, but protein subunit vaccines like Novavax's (which unfortunately has taken forever to get to market) seem to be comparably efficacious, don't have the crazy cold-chain requirements, and depend on technologies that are much more broadly understood (adjuvanted protein subunit vaccines for other diseases are already available as generics manufactured in developing-world facilities). It seems like something like that would be a better reverse-engineering starting point.
- selcuka 5y agoI believe it's the future potential of mRNA vaccines that makes it a more valuable target. They can also be used against other, non-viral diseases, such as cancer.