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This seems like a complete distraction to me. Moderna's vaccine needs to be frozen between -50C to -15C for long term storage and can be stored refrigerated for
by gautamdivgi 5y ago
This seems like a complete distraction to me. Moderna's vaccine needs to be frozen between -50C to -15C for long term storage and can be stored refrigerated for up to 30 days [1]. What WHO vaccine dependent country is the WHO targeting with this? A lot of the refrigeration requirements rule out places with poor infrastructure. It just seems like a generics making power play.
1. https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/downloads/storage-summary.pdf https://www.cdc.gov/vaccines/covid-19/info-by-product/modern...
- apendleton 5y agoIndeed, it seems like the mRNA vaccines got tons of traction because of a combination of high efficacy and first-mover advantage, but protein subunit vaccines like Novavax's (which unfortunately has taken forever to get to market) seem to be comparably efficacious, don't have the crazy cold-chain requirements, and depend on technologies that are much more broadly understood (adjuvanted protein subunit vaccines for other diseases are already available as generics manufactured in developing-world facilities). It seems like something like that would be a better reverse-engineering starting point.
- selcuka 5y agoI believe it's the future potential of mRNA vaccines that makes it a more valuable target. They can also be used against other, non-viral diseases, such as cancer.
- orangepurple 5y agoDry ice can be used to provide cooling and is relatively available or can be made available without too much difficulty so the drugs can stay cold in insulated transport 24 hours.
- gautamdivgi 5y agoThat’s literally the first thing the cdc guidance says not to do - do not place on dry ice.
- orangepurple 5y agoIt's possible to build a simple mechanical device which opens a variable size aperture in an insulated chamber to control the temperature.