Not sure exactly what you're after, but if it's FOSS then I would definitely recommend https://github.com/restic/restic https://github.com/restic/restic or http

Not sure exactly what you're after, but if it's FOSS then I would definitely recommend https://github.com/restic/restic https://github.com/restic/restic or https://git-annex.branchable.com https://git-annex.branchable.com. As others mention a lot of closed source tools offer local encryption, including Backblaze (although I believe they need your key in order to do restores, which might or might not defeat the purpose depending on your use case).