5 ms·
Farid Jalali is a gastrointestinal doctor who was an early advocate of cyproheptadine for COVID-19. His tweet-threads about why the SSRI Fluvoxamine and anti-se
by taxicabjesus 5y ago
Farid Jalali is a gastrointestinal doctor who was an early advocate of cyproheptadine for COVID-19. His tweet-threads about why the SSRI Fluvoxamine and anti-serotonin drugs are helpful to treat COVID-19 are very informative:
https://twitter.com/farid__jalali/status/1350149862457630720 https://twitter.com/farid__jalali/status/1350149862457630720
https://twitter.com/farid__jalali/status/1392559708079333379 https://twitter.com/farid__jalali/status/1392559708079333379
Dr. Jalali said at some point that the anti-viral drug Remdesivir is basically worthless for COVID-19. Molnupiravir gets headlines, but I think it's a money-grab, as no one will pay to study repurposed approved generic drugs like cyproheptadine and fluvoxamine.
(Dr. Jalali blocked me after I said something about ventilation imploding lungs, but that is literally what happens, via "nitrogen washout", as mentioned in my blog post.)
- gus_massa 5y agoIt looks like an interesting idea, but my level of biology is not good enough to be sure. There are many things that look like good ideas on paper, but have no clinical effect. For example, as you say Remdesivir is not useful against covid-19, IIRC. I remember a few clinical studies of the use of fluvoxamine against covid-19, so it's possible to study these drugs. For example see https://news.ycombinator.com/item?id=28220574 https://news.ycombinator.com/item?id=28220574 (I'm not convinced, in particular because they use the number of hospitalizations instead of the number of death.)