High performance JIT compiling VMs don't use a GIL, they use a different trick called safe points. The compiled code polls a global or per-thread variable as i

High performance JIT compiling VMs don't use a GIL, they use a different trick called safe points. The compiled code polls a global or per-thread variable as it runs (but in a very optimized way). When one thread tries to change something that might break another thread, the other threads are brought to a clean halt at specific points in the program where the full state of the abstract interpreter can be reconstructed from the stack and register state. Then the thread stacks are rewritten to force the thread back into the interpreter and the compiled code is deallocated. The result is that if you need to change something that is in practice only changed very rarely, instead of constantly locking/unlocking a global lock (very, very slow) you replace it with a polling operation (can be very fast as the CPU will execute it speculatively). However, this requires a lot of very sophisticated low level virtual machinery. The JVM has it. V8 has it. CLR has a limited form of it. Maybe PyPy does, I'm not sure? Most other runtimes do not. For the Python community, very likely the best way to upgrade performance would be to start treating CPython as stable/legacy, then support and encourage efforts like GraalPython. That way the community can re-use all the effort put into the JVM.