I'm in similar situation, not as bad as you but I have to use one hand at some points. Here are the tricks: 1. Use split keyboards 2. Use two monitors: with

I'm in similar situation, not as bad as you but I have to use one hand at some points. Here are the tricks: 1. Use split keyboards 2. Use two monitors: with 2 hand I can do alt+tab all day long but now It's harder 3. Assign hotkey to a certain applications/shortcuts Then just consitently force yourself to do that everyday. It's terrible at first but you will get use to it.