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This is the matching journal article: https://pubmed.ncbi.nlm.nih.gov/34420969/ https://pubmed.ncbi.nlm.nih.gov/34420969/ Brenowitz, W. D., Zeki Al Hazzouri, A
by tuukkah 5y ago
This is the matching journal article: https://pubmed.ncbi.nlm.nih.gov/34420969/ https://pubmed.ncbi.nlm.nih.gov/34420969/
Brenowitz, W. D., Zeki Al Hazzouri, A., Vittinghoff, E., Golden, S. H., Fitzpatrick, A. L., & Yaffe, K. (2021). Depressive Symptoms Imputed Across the Life Course Are Associated with Cognitive Impairment and Cognitive Decline. Journal of Alzheimer's disease : JAD, 83(3), 1379–1389. https://doi.org/10.3233/JAD-210588 https://doi.org/10.3233/JAD-210588
Methods: "Using a pooled study of 4 prospective cohorts (ages 20-89), we imputed adult life course depressive symptoms trajectories based on Center for Epidemiologic Studies Depression Scale-10 (CESD-10) and calculated time-weighted averages for early adulthood (ages 20-49), mid-life (ages 50-69), and late-life (ages 70-89) for 6,122 older participants. Adjusted pooled logistic and mixed-effects models estimated associations of imputed depressive symptoms with two cognitive outcomes: cognitive impairment defined by established criteria and a composite cognitive score."