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> They also note that having covid is a risk factor for myocarditis. So perhaps still worth it to take the shot. No: Absolutely not worth it to take that parti

> They also note that having covid is a risk factor for myocarditis. So perhaps still worth it to take the shot. No: Absolutely not worth it to take that particular shot, as there are others available which don't have that side effect.

mullingitover 5y ago
The data I've seen seems to show that the Moderna vaccine is the best of them in terms of long-term efficacy against breakthrough infection and hospitalization. I got Pfizer, and honestly I wish I would've had Moderna regardless of some very slim chances of myocarditis. My increased chances of getting a breakthrough infection on the Pfizer vaccine outweigh my chances of getting myocarditis on Moderna.
phnofive 5y ago
Viral myocarditis is serious but not life threatening and self-resolves in less than a year; the vaccine-induced cases are even more mild than that.
8note 5y ago
Is it likely that if both the vaccine and the virus cause it, that the symptom could be related to the spike protein itself? In that case, I'd expect all of the vaccines to have a similar risk, and it's only been spotted in one so far
- nojokes 5y ago
  It has been clearly spotted in 2 mRNA vaccines (Pfizer, Moderna). There is limited information about vector based vaccines. It is fairly clear that adverse effect is dose dependent and it may be the reason why we do not see that many with vector vaccines - immune system creates some immunity against the vector virus and actual amount of vaccine entering cells is limited. It is also evident from the limited immune response from vector vaccines.
amluto 5y ago
The best available data suggests that _that_ particular shot is rather more effective after a few months than its competitors.
not2b 5y ago
That's very unclear, since people who got Moderna are getting fewer breakthrough infections that people who got Pfizer, and are being hospitalized less (from studies by the Mayo Clinic and confirmed elsewhere). So you can't look just at side effects, you also need to look at effectiveness. They could inject you with a placebo known to be side effect free.

mullingitover 5y ago

The data I've seen seems to show that the Moderna vaccine is the best of them in terms of long-term efficacy against breakthrough infection and hospitalization. I got Pfizer, and honestly I wish I would've had Moderna regardless of some very slim chances of myocarditis. My increased chances of getting a breakthrough infection on the Pfizer vaccine outweigh my chances of getting myocarditis on Moderna.

phnofive 5y ago

Viral myocarditis is serious but not life threatening and self-resolves in less than a year; the vaccine-induced cases are even more mild than that.

8note 5y ago

Is it likely that if both the vaccine and the virus cause it, that the symptom could be related to the spike protein itself? In that case, I'd expect all of the vaccines to have a similar risk, and it's only been spotted in one so far

nojokes 5y ago
It has been clearly spotted in 2 mRNA vaccines (Pfizer, Moderna). There is limited information about vector based vaccines. It is fairly clear that adverse effect is dose dependent and it may be the reason why we do not see that many with vector vaccines - immune system creates some immunity against the vector virus and actual amount of vaccine entering cells is limited. It is also evident from the limited immune response from vector vaccines.

amluto 5y ago

The best available data suggests that _that_ particular shot is rather more effective after a few months than its competitors.

not2b 5y ago

That's very unclear, since people who got Moderna are getting fewer breakthrough infections that people who got Pfizer, and are being hospitalized less (from studies by the Mayo Clinic and confirmed elsewhere). So you can't look just at side effects, you also need to look at effectiveness. They could inject you with a placebo known to be side effect free.