If the monomer is completely unstable by itself, and wouldn't fold, I'm pretty sure 5 of them are not going to fold simultaneously into a multimer. So it would

If the monomer is completely unstable by itself, and wouldn't fold, I'm pretty sure 5 of them are not going to fold simultaneously into a multimer. So it would be a good guess that the monomers are going to fold first into something that at least looks roughly like the final product and then assemble and change configuration. But no I haven't read any articles studying this in detail. I do recall seeing studies on the evolution of oligomers, where the monomer exists by itself but evolves to polymerize at the expense of its monomeric stability.