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Sure, getting vaccinated after one recovers from an infection imparts the highest level of protection by that wasn't the GP's point. A prior infection imparts a

by unmole 5y ago

Sure, getting vaccinated after one recovers from an infection imparts the highest level of protection by that wasn't the GP's point. A prior infection imparts a much higher level of protection against future infections than any vaccine that we currently have.

Retric 5y ago
Possibly, though positive Covid tests aren’t a guarantee of an actual infection which might be why some studies showed vaccination was more effective. Alternatively, having survived the first infection says more about the individual than getting a vaccination. Which is yet another way this stuff gets tricky.
- unmole 5y ago
  > some studies showed vaccination was more effective Could you point me to them? I'm unable to find any.
  - Retric 5y ago
    Here’s one showing prior infections or at least prior positive test results failing to result in long term immunity. https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article
    - angelzen 5y ago
      The linked article does not study long term reinfection rates, it studies systemic antibody response. Unfortunately, the topic of long-term covid antibody research is a difficult area: both exponential antibody decay and antibody location are relevant. Extrapolating epidemiological conclusions from small population antibody studies is reaching.
      - Retric 5y ago
        Population studies run into different issues you want both. I recall an early study showing vaccination being significantly more effective, but that’s before current variants showed up etc. Really you can’t draw accurate conclusions from any one study but multiple studies give you a better picture of what’s going on. Large numbers of people falsely believe they had COVID, people who survived COVID are healthier than the general population because the other option is death, the most common infection doesn’t get a strong immune response, vaccine recipients tend to be older and in worse health etc. That said, an otherwise healthy person who got very sick from COVID and got multiple high quality tests verifying exposure likely does have a significantly better long term protection. But, that’s not representative of the general population that had COVID.

by unmole 5y ago

Retric 5y ago

Possibly, though positive Covid tests aren’t a guarantee of an actual infection which might be why some studies showed vaccination was more effective. Alternatively, having survived the first infection says more about the individual than getting a vaccination. Which is yet another way this stuff gets tricky.

unmole 5y ago
> some studies showed vaccination was more effective Could you point me to them? I'm unable to find any.
- Retric 5y ago
  Here’s one showing prior infections or at least prior positive test results failing to result in long term immunity. https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article
  - angelzen 5y ago
    The linked article does not study long term reinfection rates, it studies systemic antibody response. Unfortunately, the topic of long-term covid antibody research is a difficult area: both exponential antibody decay and antibody location are relevant. Extrapolating epidemiological conclusions from small population antibody studies is reaching.
    - Retric 5y ago
      Population studies run into different issues you want both. I recall an early study showing vaccination being significantly more effective, but that’s before current variants showed up etc. Really you can’t draw accurate conclusions from any one study but multiple studies give you a better picture of what’s going on. Large numbers of people falsely believe they had COVID, people who survived COVID are healthier than the general population because the other option is death, the most common infection doesn’t get a strong immune response, vaccine recipients tend to be older and in worse health etc. That said, an otherwise healthy person who got very sick from COVID and got multiple high quality tests verifying exposure likely does have a significantly better long term protection. But, that’s not representative of the general population that had COVID.