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The risk of psychosis is higher in moderate coffee or alcohol use than it is with cannabis. The touted psychosis risk is mostly FUD: it only applies to those ge

The risk of psychosis is higher in moderate coffee or alcohol use than it is with cannabis. The touted psychosis risk is mostly FUD: it only applies to those genetically predisposed to schizophrenia, which is such a strong predisposition that the people with those genes will develop symptoms sooner or later. They also definitely need to avoid coffee, tobacco and alcohol, but somehow there’s not so much ranting and raving going on about that.

hackingforfun 5y ago
I disagree, especially considering high THC strains. In general, coffee, tobacco and alcohol are milder. People can do stupid stuff after having too much alcohol, but I'm not sure I would consider that psychosis. Having too much THC can make someone feel a bit crazy (or maybe a lot crazy). It can even be somewhat psychedelic at higher doses, so there's just some variability there. The thing is that THC can also make people feel pretty relaxed, so they wouldn't necessarily want to go out and do something stupid, but I'm just saying that it isn't a guarantee. I think there is some risk, at least for acute episodes, and I personally don't think it's just FUD.
- eurasiantiger 5y ago
  The claim is that THC somehow causes craziness, and it’s usually paired with claims that CBD inhibits those effects. However, see this: https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-020-00051-z https://jcannabisresearch.biomedcentral.com/articles/10.1186... > Fixed effects regressions showed that, controlling for time-invariant user characteristics, mid and high tetrahydrocannabinol (THC) levels were the primary independent predictor of increased symptom relief, and that when broken out by symptom type, this effect was only statistically significant for our largest sample of users, those reporting anxiety rather than agitation/irritability or stress. Cannabidiol (CBD) levels were generally not associated with changes in symptom intensity levels. In a minority of cannabis use sessions (< 13%), cannabis users reported anxiogenic-related negative side effects (e.g., feeling anxious, irritable, paranoid, rapid pulse, or restless), whereas in a majority of sessions (about 66%), users reported positive anxiolytic side effects (e.g., feeling chill, comfy, happy, optimistic, peaceful, or relaxed). > higher THC levels were the strongest predictors of relief
  - hackingforfun 5y ago
    I agree about THC being a symptom reliever. I myself don't care much for CBD, although I have heard it works for some people. Anyway, I'm just not sure I'd put cannabis in the same class as alcohol, tobacco and coffee, in terms of psychosis risk, although I don't think that cannabis should be federally illegal though either.
    - eurasiantiger 5y ago
      I wouldn’t put them in the same category either; psychosis is much more likely with those than with cannabis.
Fnoord 5y ago
As someone with autism diagnosis who had multiple psychosis due to cannabis yet none from alcohol and coffee, I respectfully disagree.
- eurasiantiger 5y ago
  You already stated that you are not neurotypical, so why would your anecdotal experience count in a case that concerns everyone? Also, how can you be certain your psychoses were not caused by concommittant use of coffee/alcohol and cannabis? Especially coffee, since it contains monoamine oxidase inhibitors that are known to be stored in brain fatty tissues for months after cessation of use.

hackingforfun 5y ago

I disagree, especially considering high THC strains. In general, coffee, tobacco and alcohol are milder. People can do stupid stuff after having too much alcohol, but I'm not sure I would consider that psychosis. Having too much THC can make someone feel a bit crazy (or maybe a lot crazy). It can even be somewhat psychedelic at higher doses, so there's just some variability there. The thing is that THC can also make people feel pretty relaxed, so they wouldn't necessarily want to go out and do something stupid, but I'm just saying that it isn't a guarantee. I think there is some risk, at least for acute episodes, and I personally don't think it's just FUD.

eurasiantiger 5y ago
The claim is that THC somehow causes craziness, and it’s usually paired with claims that CBD inhibits those effects. However, see this: https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-020-00051-z https://jcannabisresearch.biomedcentral.com/articles/10.1186... > Fixed effects regressions showed that, controlling for time-invariant user characteristics, mid and high tetrahydrocannabinol (THC) levels were the primary independent predictor of increased symptom relief, and that when broken out by symptom type, this effect was only statistically significant for our largest sample of users, those reporting anxiety rather than agitation/irritability or stress. Cannabidiol (CBD) levels were generally not associated with changes in symptom intensity levels. In a minority of cannabis use sessions (< 13%), cannabis users reported anxiogenic-related negative side effects (e.g., feeling anxious, irritable, paranoid, rapid pulse, or restless), whereas in a majority of sessions (about 66%), users reported positive anxiolytic side effects (e.g., feeling chill, comfy, happy, optimistic, peaceful, or relaxed). > higher THC levels were the strongest predictors of relief
- hackingforfun 5y ago
  I agree about THC being a symptom reliever. I myself don't care much for CBD, although I have heard it works for some people. Anyway, I'm just not sure I'd put cannabis in the same class as alcohol, tobacco and coffee, in terms of psychosis risk, although I don't think that cannabis should be federally illegal though either.
  - eurasiantiger 5y ago
    I wouldn’t put them in the same category either; psychosis is much more likely with those than with cannabis.

Fnoord 5y ago

As someone with autism diagnosis who had multiple psychosis due to cannabis yet none from alcohol and coffee, I respectfully disagree.

eurasiantiger 5y ago
You already stated that you are not neurotypical, so why would your anecdotal experience count in a case that concerns everyone? Also, how can you be certain your psychoses were not caused by concommittant use of coffee/alcohol and cannabis? Especially coffee, since it contains monoamine oxidase inhibitors that are known to be stored in brain fatty tissues for months after cessation of use.