4 ms·
Therapeutic index for Tylenol is 2. That's already much better than NSAIDs, which are often already very toxic at usual dosage (400mg ibuprofen) in diabetics, s
by rscho 5y ago
Therapeutic index for Tylenol is 2. That's already much better than NSAIDs, which are often already very toxic at usual dosage (400mg ibuprofen) in diabetics, senior citizens, children, etc. The big difference is that with acute liver damage you are feeling very sick and die quickly, while with kidney failure you feel normal and die very slowly. So, what's worse?
Additionally, it's no wonder that it's a paediatrician speaking, because many Tylenol intoxications are actually intentional in children (suicide). It's one of the most common suicide plan in teenagers.