4 ms·
if tylenol was a newly created drug, there is no chance it would have so few restrictions on its usage.
by throwaway2048 5y ago
if tylenol was a newly created drug, there is no chance it would have so few restrictions on its usage.
- lostlogin 5y agoImaging trying to get alcohol past regulators.
- ekianjo 5y agoI would not be so sure. Regulatory agencies have recently approved AD treatment without any sort of evidence. In 2021.
- np_tedious 5y agoTrue, but not quite relevant. That is a prescription drug which does/will therefore have quite a few more restrictions than over the counter Tylenol
- ekianjo 5y agoIt's relevant in the sense that you can't trust the FDA for anything scientific anymore. It's been hacked.
- deleted 5y ago[deleted]
- refurb 5y agoI disagree. Acetaminophen use is incredibly widespread yet few end up in liver failure. Without acetaminophen your only option for pain relief without going to much stronger drugs would be the NSAIDS like aspirin or ibuprofen. While not toxic to your liver, if you take them often enough you’ll end up with GI bleeding pretty reliably.
- robbedpeter 5y agoThere is little to no evidence that Tylenol works as a pain reliever - its analgesic effects are comparable to placebo. There's lots of evidence that it doesn't work, and there's no accepted or plausible mechanism of action. It doesn't work. It is the leading cause of liver failure in western societies. And yet the "common knowledge" of its utility surpasses those facts among doctors and pharmacists. They keep prescribing it and adding it to other medicines, but there's no good medical reasons to do so.
- maccard 5y agoThat's a lot of bold claims in one post. Have you uany studies to back up the claim that it doesn't work, it's the leadong cause of liver failure in western societies, or that there's no good reason to add it to other medicines?
- satellite2 5y agoYou might be mistaking it with other substances. There is a massive body of evidence showing that it's far more effective than placebo. There are even recent tentative evidence that show it increases risk taking behaviours and reduce emotional response to various stimulus.
- robbedpeter 5y agohttps://www.acsh.org/news/2017/09/18/tylenol-isnt-so-safe-least-it-works-right-11827 https://www.acsh.org/news/2017/09/18/tylenol-isnt-so-safe-le... You can find the studies with scihub. Tylenol doesn't seem to work for fever or anti inflammatory purposes either. It's great at hurting and killing people, though, in overdose and chronic use scenarios.
- refurb 5y agoKeep in mind it’s not trivial to run pain studies at all. Placebos have a strong effect in most trials and unless you get into the moderate to severe pain category, patients subjective experience can dominate. Small changes to a trial can completely blow it up. Same with antidepressants or anything where the trial outcome is a subjective measure by the patient.
- feanaro 5y ago> Tylenol doesn't seem to work for fever What? Not sure what alternate universe we're talking about, but paracetamol definitely works on fever in this one.