But that's not connected to fifths tuning. It can happen with any tuning (one “trick” with a dual neck 6/12 string electric guitar is to tune the strings on the

But that's not connected to fifths tuning. It can happen with any tuning (one “trick” with a dual neck 6/12 string electric guitar is to tune the strings on the 12-string neck to each of the diatonic pitches so they resonate with whatever note is played on the 6-string neck, and then of course there are the sympathetic strings on Indian stringed instruments which have a similar function). Curiously, while orchestral strings tend to be more comfortable in the sharp keys, as a double bass player, I was equally at home (if not more so) in the flat keys that tend to be favored by winds.