Based on a single in vitro study. In isolation such a study is good indication that in vivo dosing is impractical (though a 35x dose is still far under the ld50

Based on a single in vitro study. In isolation such a study is good indication that in vivo dosing is impractical (though a 35x dose is still far under the ld50 for ivermectin[0]), but given that there are dozens of studies suggesting positive effect and the complexity of human/viral biology, the effective dose in vivo may be far lower than the in vitro study indicated. To be clear I'm not suggesting with certainty that ivermectin works, but I need a better explanation than "these 2 dozen+ studies are all low quality and/or use manipulated/fake data" before I'm willing to rule it out and jump on this bandwagon. 0. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835698/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835698/ [see section titled Toxicology]