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> What about your body only making limited, synthetic antigen antibodies instead of the better, more flexible natural ones in response to even more out of band

> What about your body only making limited, synthetic antigen antibodies instead of the better, more flexible natural ones in response to even more out of band gamma or mu strains? These are entirely unknown problems we're in the process of researching and for better or worse, we're the guinea pigs. well, scores and scores of people not dying from a virus that's killed millions is why. those "limited" (and not synthetic those are real antibodies against real antigens) are working very well unless you believe that the current world wide vaccine drive is ineffectual against all data to the contrary... the vaccines have been a huge success against the coronavirus. and you are the guinea pig already... just in the control group that's dying left and right at a very high pace and also leaving lots of people with "long covid" that is also giving them long term, yet unknown side effects. > It should be telling that doctors and nurses who have been watching covid patients die still often come to the conclusion that the vaccine isn't for them and is too risky. it is telling that there are unreasonable people out there however vanishingly small a number. In one recent survey of doctors 96% of them had gotten the vaccine. 45% of the remaining 4% were still planning on getting it. so that's about 2% of doctors that are not planing on taking it... i'd say that's an overwhelming number of doctors that are getting the vaccine. mind you that 2% number includes people that never are face to face with people dying of the disease on a daily basis in all likelihood. it is very telling when the smartest people in the room are all taking the vaccine. finally, that Israeli study is misinterpreted... it doesn't matter if you get infected as much after being vaccinated. what matters is if you get very sick after you get infected and to that end the vaccines are wildly successful. and even then the absolute numbers of people getting sick from the strain is very small; over 650,000 people in america have died from covid and the vast majority of them are unvaccinated. full stop.

hajile 5y ago
Israel's Health Ministry has clearly stated that the vaccine is 39% effective against Delta strain [0] at preventing disease. Think about that, according to Israel, 61% of vaccinated people are catching full-blown COVID and by implication, some lesser amount are catching an asymptomatic version. The Gamma and Mu strains are known to be even more resistant to the vaccine. People are so desperate for their fear to abate that they'll put on the blinders while trying to convince themselves of all kinds of things. With at least 61% of vaccinated people getting a virus with one of the highest r0 around, the vaccine is 100% ineffective at killing transmission. The virus swims around many millions of vaccinated immune systems mutating until it finally finds something that works around the vaccine antibody. This is contrary to the media's anti-science garbage about unvaccinated being the cause of a virus mutating (why would it need to mutate around the vaccine antibody if they don't have any in their system?). Paired with evidence that natural immunity is up to 27x better, the picture is pretty clear. The vaccine antibody is a response to a synthetic antigen rather than the natural one. The resulting antibody targeting the synthetic antigen (why I specifically referred to it as a "synthetic antigen antibody") is not as flexible against the actual disease. My greatest hope at this point is that vaccinated people catching Delta are slowing the spread with the inefficient antibodies while developing natural antibodies, but I've seen zero studies about this. If this is not the case, then I fear we've kicked the danger can down the road and made it even worse. In the worst case, an ADE effect develops (not theoretical -- this was one of the biggest concerns/problems in previous SARS/MERS vaccine attempts) and 50+% of vaccinated people die. > it is telling that there are unreasonable people out there however vanishingly small a number. In one recent survey of doctors 96% of them had gotten the vaccine. 45% of the remaining 4% were still planning on getting it. so that's about 2% of doctors that are not planing on taking it... i'd say that's an overwhelming number of doctors that are getting the vaccine. Don't mistake getting and wanting. Most of my family are in the medical field. Some travel all across the country. Huge amounts of people had to be threatened with losing their livelihood before they got the vaccine. My sibling has had a couple months of symptoms from their vaccine (most likely because they'd already caught COVID and severe reactions are much more likely in that case). In truth, it is anti-science to require the vaccine from those with natural antibodies as we now know they have strictly better antibodies. Then again, vaccination seems more about politics than science. [0] https://www.cnbc.com/2021/07/23/delta-variant-pfizer-covid-vaccine-39percent-effective-in-israel-prevents-severe-illness.html https://www.cnbc.com/2021/07/23/delta-variant-pfizer-covid-v...
- weaksauce 5y ago
  > Think about that, according to Israel, 61% of vaccinated people are catching full-blown COVID and by implication, some lesser amount are catching an asymptomatic version. the fact that you think that breakthrough cases are somehow rare in a highly vaccinated population is nuts. of course the majority of cases will be vaccinated people in a highly vaccinated population. and also, I read the presentation it was based off and the confidence interval on that statistic is off the charts variable. > With at least 61% of vaccinated people getting a virus with one of the highest r0 around, the vaccine is 100% ineffective at killing transmission. That's not how those statistics work. The vaccine is not "100% ineffective at killing transmission". The nature of how the immune system works is such that there is a drop off in free antibodies in your blood stream that are able to prevent infection over time. that's 100% how it works. the fact that there is less serious cases of covid with shorter infectious periods of time with less strain on the ICU systems mean the vaccines are working. I get you are scared of the vaccine for some reason or another but the mental gymnastics are hindering our ability to move on as a society. the vaccines allow covid to become endemic like the cold that just makes most people feel a bit shitty for a few days vs. completely overwhelm the ICUs and kill people for unrelated things.

hajile 5y ago

Israel's Health Ministry has clearly stated that the vaccine is 39% effective against Delta strain [0] at preventing disease. Think about that, according to Israel, 61% of vaccinated people are catching full-blown COVID and by implication, some lesser amount are catching an asymptomatic version. The Gamma and Mu strains are known to be even more resistant to the vaccine. People are so desperate for their fear to abate that they'll put on the blinders while trying to convince themselves of all kinds of things. With at least 61% of vaccinated people getting a virus with one of the highest r0 around, the vaccine is 100% ineffective at killing transmission. The virus swims around many millions of vaccinated immune systems mutating until it finally finds something that works around the vaccine antibody. This is contrary to the media's anti-science garbage about unvaccinated being the cause of a virus mutating (why would it need to mutate around the vaccine antibody if they don't have any in their system?). Paired with evidence that natural immunity is up to 27x better, the picture is pretty clear. The vaccine antibody is a response to a synthetic antigen rather than the natural one. The resulting antibody targeting the synthetic antigen (why I specifically referred to it as a "synthetic antigen antibody") is not as flexible against the actual disease. My greatest hope at this point is that vaccinated people catching Delta are slowing the spread with the inefficient antibodies while developing natural antibodies, but I've seen zero studies about this. If this is not the case, then I fear we've kicked the danger can down the road and made it even worse. In the worst case, an ADE effect develops (not theoretical -- this was one of the biggest concerns/problems in previous SARS/MERS vaccine attempts) and 50+% of vaccinated people die. > it is telling that there are unreasonable people out there however vanishingly small a number. In one recent survey of doctors 96% of them had gotten the vaccine. 45% of the remaining 4% were still planning on getting it. so that's about 2% of doctors that are not planing on taking it... i'd say that's an overwhelming number of doctors that are getting the vaccine. Don't mistake getting and wanting. Most of my family are in the medical field. Some travel all across the country. Huge amounts of people had to be threatened with losing their livelihood before they got the vaccine. My sibling has had a couple months of symptoms from their vaccine (most likely because they'd already caught COVID and severe reactions are much more likely in that case). In truth, it is anti-science to require the vaccine from those with natural antibodies as we now know they have strictly better antibodies. Then again, vaccination seems more about politics than science. [0] https://www.cnbc.com/2021/07/23/delta-variant-pfizer-covid-vaccine-39percent-effective-in-israel-prevents-severe-illness.html https://www.cnbc.com/2021/07/23/delta-variant-pfizer-covid-v...

weaksauce 5y ago
> Think about that, according to Israel, 61% of vaccinated people are catching full-blown COVID and by implication, some lesser amount are catching an asymptomatic version. the fact that you think that breakthrough cases are somehow rare in a highly vaccinated population is nuts. of course the majority of cases will be vaccinated people in a highly vaccinated population. and also, I read the presentation it was based off and the confidence interval on that statistic is off the charts variable. > With at least 61% of vaccinated people getting a virus with one of the highest r0 around, the vaccine is 100% ineffective at killing transmission. That's not how those statistics work. The vaccine is not "100% ineffective at killing transmission". The nature of how the immune system works is such that there is a drop off in free antibodies in your blood stream that are able to prevent infection over time. that's 100% how it works. the fact that there is less serious cases of covid with shorter infectious periods of time with less strain on the ICU systems mean the vaccines are working. I get you are scared of the vaccine for some reason or another but the mental gymnastics are hindering our ability to move on as a society. the vaccines allow covid to become endemic like the cold that just makes most people feel a bit shitty for a few days vs. completely overwhelm the ICUs and kill people for unrelated things.