3 ms·
Placebo effect. CBD and THC are not well absorbed topically and there's no data on transdermal bioavailability, so the effective dosage would be unscientific an
by stooliepidgin 5y ago
Placebo effect. CBD and THC are not well absorbed topically and there's no data on transdermal bioavailability, so the effective dosage would be unscientific and unknown. The majority of CBD creams fall within the category of snake oil to dupe consumers into spending money just as they do on beauty products. THC absorption by the skin is very low.
https://pubmed.ncbi.nlm.nih.gov/12100860/ https://pubmed.ncbi.nlm.nih.gov/12100860/
- risedotmoe 5y agoWhile some CBD products I do believe to be snake oil, what basis do you have for products containing both CBD and THC to only being effective as a placebo? CBD isn’t truly effective without THC and the THC is what basically turns the snake oil into a legitimately effective product. Additionally, everyone’s sensitivity to marijuana differs and while skin absorption may be “low” that does not mean none and even the effects of a low amount can be felt.
- stooliepidgin 5y ago> what basis do you have for products containing both CBD and THC to only being effective as a placebo Read the article. Because without carrier molecules, cannabinoids cannot be effectively absorbed to do much more than provide minor, dermal-area effects. There's no getting high, and not much deep penetration of anything. > CBD isn’t truly effective without THC. Truly what? Based on what evidence? 10 mg of pure CBD in a lipid sublingual tincture is calming if you've ever tried it. Easily distinguishable from placebo.